TY - JOUR T1 - Long-Term Domiciliary Noninvasive Ventilation for COPD JF - Respiratory Care SP - 1120 LP - 1127 DO - 10.4187/respcare.09052 VL - 66 IS - 7 AU - Robert L Owens Y1 - 2021/07/01 UR - http://rc.rcjournal.com/content/66/7/1120.abstract N2 - COPD can lead to abnormalities in oxygenation as well as ventilation. Thanks to pioneering work by Dr Thomas Petty, supplemental oxygen therapy has been shown to improve morbidity and mortality for individuals with COPD and severe daytime hypoxemia. However, efforts to augment ventilation have been less uniformly successful. Recent studies employing a so-called high-intensity noninvasive ventilation strategy, which used high inspiratory pressures and backup breathing frequency to reduce arterial carbon dioxide levels, have shown improved quality of life and reduced mortality. Thus, efforts are underway to better identify and treat patients with COPD who might benefit from noninvasive ventilation, though many practical questions remain. ER -