RT Journal Article SR Electronic T1 Body Mass Index and Hospital Readmissions for COPD JF Respiratory Care FD American Association for Respiratory Care SP 3606921 VO 66 IS Suppl 10 A1 Abdullah Mayof Alanazi A1 Saleh Alqarni A1 Tareq Alotabi A1 Taha Ismaeil YR 2021 UL http://rc.rcjournal.com/content/66/Suppl_10/3606921.abstract AB Background: Adults with COPD are predisposed to frequent complications related to their progressive disease which increases their hospitalizations. As elderly with COPD ages, the risk of hospital readmission increases; however, it is not clear what is the effect of body mass index (BMI) among elderly Saudi with COPD. Especially, within a cultural framework as the older tends to be served and less physically active to indirectly predispose him/her to abnormally high BMI. Methods: Data from a random represented sample of 300 Saudi adults with COPD were retrieved from the medical record of a tertiary care hospital in Saudi Arabia after the approval of the institutional review board. Several variables were collected including demographics, hospital readmission, comorbidities, and BMIs. Logistic regression and Andrew Hayes’ moderation analysis were used to predict hospital readmission and test the moderation (interaction) effect of BMI with hospital readmission predictors among adults with COPD. Results: Among our hypothesized predictors, we have found that age and cardiovascular disease with COPD increases the odds of hospital readmissions (aOR = 1.025, 95% CI [1.004–1.046], and aOR = 2.374, 95% CI [1.092–5.164], respectively). However, those with COPD and musculoskeletal disorders were less likely to be readmitted into hospitals (aOR = 0.496, 95% CI [0.247–0.997]. Among the significant predictors, BMI significantly moderated the relation of age with hospital readmission (B = 0.002, SE = 0.001, P = 0.041). Conclusions: The burden of COPD-related complications remains public health and clinical dilemmas; one of which is the hospital readmission of COPD. We revealed, however, that the older and higher BMI those with COPD, the greater the risk of hospital readmission. This moderation finding signifies the necessity of dietary and exercise prescriptions to elderly with COPD in their action and discharge plans to avoid abnormally high BMI and sedentary behaviors they may increase the risk of hospital readmission.