RT Journal Article SR Electronic T1 The effect of filters on CPAP delivery by helmet JF Respiratory Care FD American Association for Respiratory Care SP respcare.09822 DO 10.4187/respcare.09822 A1 Daniele Privitera A1 Nicolò Capsoni A1 Francesco Zadek A1 Paolo Vailati A1 Chiara Airoldi A1 Mattia Cozzi A1 Federico Pierotti A1 Roberto Fumagalli A1 Andrea Bellone A1 Thomas Langer YR 2022 UL http://rc.rcjournal.com/content/early/2022/03/01/respcare.09822.abstract AB Background: When helmet continuous positive airway pressure (H-CPAP) is performed using a Venturi system, filters are frequently interposed in the respiratory circuit to reduce noise within the helmet. The effect of the interposition of these filters on delivered fresh gas flow and the resulting inspired fraction of oxygen (FiO2) is currently unknown.Methods: In a bench study, two different Venturi systems (Whisperflow and Harol) were used to generate three different gas flow/FiO2 couples (80 L/min-FiO2 0.6; 100 L/min-FiO2 0.5; 120 L/min- FiO2 0.4). Different combinations of filters were applied at the flow generator input line and/or at the helmet inlet port. Two types of filters were used for this purpose: a heat and moister exchanger filter and an electrostatic filter. The setup without filters was used as Baseline. Gas flow and FiO2 were measured for each setup.Results: Compared to Baseline, the interposition of filters reduced the gas flow between 1 and 13% (p<0.01). The application of a filter at the Venturi system or at the Helmet generated a comparable flow reduction (-3 ± 2% vs. -4 ± 2%, p=0.12), while a greater flow reduction (-7 ± 4%) was observed when filters were applied at both sites (p<0.001). An increase in FiO2 up to 5% was observed with filters applied. A strong inverse linear relationship (p<0.001) was observed between the resulting gas flow and FiO2.Conclusions: The use of filters during H-CPAP reduces the flow delivered to the helmet and, consequently, modifies FiO2. If filters are applied, an adequate gas flow should be administered to guarantee a constant CPAP during the entire respiratory cycle and avoid CO2 rebreathing. Moreover, it might be important to measure the effective FiO2 delivered to the patient to guarantee a precise assessment of oxygenation.