TY - JOUR T1 - The Changing Definition and Perception of COPD JF - Respiratory Care SP - 750 LP - 755 DO - 10.4187/respcare.10059 VL - 67 IS - 6 AU - David M Mannino Y1 - 2022/06/01 UR - http://rc.rcjournal.com/content/67/6/750.abstract N2 - COPD remains one of the leading causes of death worldwide. The impact of smoking and air pollution remain important causative factors. Traditional classification of COPD includes the overlap of emphysema, chronic bronchitis and asthma. More recently the COPDGene definition includes the terms possible, probable and definite COPD. These are supported by findings from exposures, symptoms, spirometry and radiologic imaging. This new approach can lead to earlier diagnosis and modification of risk factors, earlier therapeutic intervention and improved treatments of established disease. ER -