TY - JOUR T1 - Comparison of Airway Clearance Therapies for Cystic Fibrosis: A Cochrane Review Summary With Commentary JF - Respiratory Care SP - 889 LP - 892 DO - 10.4187/respcare.10050 VL - 67 IS - 7 AU - L Denise Willis Y1 - 2022/07/01 UR - http://rc.rcjournal.com/content/67/7/889.abstract N2 - Several methods exist for airway clearance therapy in people with cystic fibrosis including both devices and techniques. Some of the common modalities include conventional chest physical therapy (CPT), active cycle of breathing, autogenic drainage, positive expiratory pressure (PEP) therapy, high-frequency chest compression, and oscillating devices. For devices, there are then many choices of different brands and models. Exercise is also considered a method of airway clearance. Although there are multiple options for airway clearance therapy, the objective to clear airway mucus is mutual for all modalities. The choice of therapy is dependent upon many factors including availability, cost, ability, and age of the user as well as personal preference. Some methods do not require assistance or active participation from the recipient such as CPT or high-frequency chest compression, whereas other therapies such as active cycle of breathing, autogenic drainage, and PEP rely solely on individual ability to perform therapy.A recent Cochrane Review compared airway clearance techniques for cystic fibrosis to evaluate the effectiveness and safety of different modalities.1 Airway clearance is a vital component in managing lung disease in cystic fibrosis to combat chronic infection and inflammation. The purpose of this commentary is to discuss the Cochrane Review “Airway Clearance Techniques for Cystic Fibrosis: an overview of Cochrane Systematic Reviews” by Wilson et al1 from a respiratory perspective, published by Cochrane Cystic Fibrosis and Genetic Disorders Group. This Cochrane Corner is produced in agreement with Respiratory Care by Cochrane Rehabilitation with views of the review summary author in the implications for practice section.The aim of this Cochrane Review was to summarize the evidence regarding effectiveness and safety of airway clearance methods in individuals with cystic fibrosis.The authors of this overview analyzed Cochrane Systematic Reviews of randomized controlled trials or quasi-randomized controlled trials that … Correspondence: L Denise Willis MSc RRT RRT-NPS AE-C FAARC. E-mail: WillisLD{at}archildrens.org ER -