TY - JOUR T1 - Relationship Between Depression in Patients With COPD and the Percent of Predicted FEV<sub>1</sub>, BODE Index, and Health-Related Quality of Life JF - Respiratory Care SP - 334 LP - 339 DO - 10.4187/respcare.01844 VL - 58 IS - 2 AU - Asuka Iguchi AU - Hideaki Senjyu AU - Yoshika Hayashi AU - Rumi Kanada AU - Shoko Iwai AU - Sumihisa Honda AU - Chika Kitagawa AU - Hiroki Ozawa AU - Naoto Rikitomi Y1 - 2013/02/01 UR - http://rc.rcjournal.com/content/58/2/334.abstract N2 - BACKGROUND: We investigated the prevalence of depression among patients with COPD treated in long-term in-patient rehabilitation facilities, using the Center for Epidemiologic Studies Depression scale (CES-D). Furthermore, the relationship between the severity of air-flow obstruction (the percent of predicted FEV1), BODE (body mass index, degree of air-flow obstruction, dyspnea, exercise capacity) index, health-related quality of life (St George's Respiratory Questionnaire [SGRQ]), and depression were investigated. METHODS: We recruited 74 in-patients (64 males, 10 females) with COPD. The mean age of the subjects was 72.7 years (range 52–85 y). Subjects completed the CES-D, and measurements were made of pulmonary function, body mass index, Modified Medical Research Council dyspnea scale, 6-min walk test (6MWT), and SGRQ. RESULTS: Depression was evident in 48.6% (n = 36) of the subjects. A weak correlation was found between the CES-D scores and the percent of predicted FEV1. The prevalence of depression showed a significant association with BODE stage. Scores for the SGRQ activity and impacts domains, and total SGRQ score were significantly worse in the subjects who were depressed. CONCLUSIONS: We found a high prevalence of depression among patients with stable COPD treated in long-term in-patient rehabilitation facilities. Depression among these patients, as measured by the CES-D, was associated with greater impairment in respiratory function and with poorer Modified Medical Research Council dyspnea scale and SGRQ scores. The prevalence of depression increased with BODE stage. ER -