RT Journal Article SR Electronic T1 COVID-19 Lessons Learned: Prone Positioning With and Without Invasive Ventilation JF Respiratory Care FD American Association for Respiratory Care SP 1011 OP 1021 DO 10.4187/respcare.10141 VO 67 IS 8 A1 Scott, J Brady A1 Weiss, Tyler T A1 Li, Jie YR 2022 UL http://rc.rcjournal.com/content/67/8/1011.abstract AB Prone positioning (PP) has been used extensively for patients requiring invasive mechanical ventilation for hypoxemic respiratory failure during the COVID-19 pandemic. Evidence suggests that PP was beneficial during the pandemic, as it improves oxygenation and might improve chances of survival, especially in those with a continuum of positive oxygenation responses to the procedure. Additionally, the pandemic drove innovation regarding PP, as it brought attention to awake PP (APP) and the value of an interdisciplinary team approach to PP during a pandemic. APP appears to be safe and effective at improving oxygenation; APP may also reduce the need for intubation in patients requiring advanced respiratory support like high-flow nasal cannula or noninvasive ventilation. Teams specifically assembled for PP during a pandemic also appear useful and can provide needed assistance to bedside clinicians in the time of crisis. Complications associated with PP can be mitigated, and a multidisciplinary approach to reduce the incidence of complications is recommended.