RT Journal Article SR Electronic T1 Caregiver Burden Is Associated With the Physical Function of Individuals on Long-Term Oxygen Therapy JF Respiratory Care FD American Association for Respiratory Care SP 1413 OP 1419 DO 10.4187/respcare.09619 VO 67 IS 11 A1 Luciana AS Jesus A1 Carla Malaguti A1 Deborah G Evangelista A1 Felipe M Azevedo A1 Brena P França A1 Larissa T Santos A1 Maycon M Reboredo A1 Annemarie L Lee A1 Laura A Cabral A1 Leandro F Cabral A1 Anderson José A1 Cristino C Oliveira YR 2022 UL http://rc.rcjournal.com/content/67/11/1413.abstract AB BACKGROUND: The influence of physical function of individuals on long-term oxygen therapy (LTOT) on caregiver burden is underexplored. This study investigated the association of caregiver burden with physical function of individuals on LTOT and the association between caregiver’s burden and quality of life.METHODS: This was a cross-sectional study. Informal caregivers were assessed for burden using the Caregiver Burden Inventory (CBI), the European Quality of Life 5 Dimension questionnaire index (EQ-5D index) and its Visual Analog Scale (EQ-VAS). Physical function of subjects on LTOT was assessed by dyspnea, activities of daily living (ADLs), and mobility. Univariate and multivariate linear regression models were explored.RESULTS: Fifty-four caregivers (54.7 ± 16.1 y, 74.1% female) were included. CBI total score was correlated with subject’s dyspnea (r = 0.369, P = .006) and ADLs (r = 0.300, P = .03). In the multivariate regression models, subject’s physical function limitation due to dyspnea explained 26.4% of the CBI total score variance (P = .005). In the CBI dimension analysis, the time-dependence caregiver burden was correlated with subject’s dyspnea (r = 0.335, P = .01), ADLs (r = 0.436, P = .001), and mobility (r = −0.415, P = .002). CBI developmental and physical caregiver burden were correlated with dyspnea (r = 0.309, P = .02; r = 0.363, P = .007) and ADLs (r = 0.274, P = .045; r = 0.299, P = .03). Emotional caregiver burden was correlated with dyspnea (r = 0.333, P = .01). Higher CBI total score was correlated with worse quality of life on EQ-5D index (rs= −0.374, P = .005) and EQ-VAS (rs= −0.494, P = .001) in caregivers.CONCLUSIONS: Increased caregiver burden was associated with higher physical limitation due to dyspnea and dependence in ADLs of individuals on LTOT. The increased burden was associated with a worse caregiver’s quality of life.