PT - JOURNAL ARTICLE AU - Luján, Manel AU - Sogo, Ana AU - Pomares, Xavier AU - Monsó, Eduard AU - Sales, Bernat AU - Blanch, Lluís TI - Effect of Leak and Breathing Pattern on the Accuracy of Tidal Volume Estimation by Commercial Home Ventilators: A Bench Study AID - 10.4187/respcare.02010 DP - 2013 May 01 TA - Respiratory Care PG - 770--777 VI - 58 IP - 5 4099 - http://rc.rcjournal.com/content/58/5/770.short 4100 - http://rc.rcjournal.com/content/58/5/770.full AB - BACKGROUND: New home ventilators are able to provide clinicians data of interest through built-in software. Monitoring of tidal volume (VT) is a key point in the assessment of the efficacy of home mechanical ventilation. OBJECTIVE: To assess the reliability of the VT provided by 5 ventilators in a bench test. METHODS: Five commercial ventilators from 4 different manufacturers were tested in pressure support mode with the help of a breathing simulator under different conditions of mechanical respiratory pattern, inflation pressure, and intentional leakage. Values provided by the built-in software of each ventilator were compared breath to breath with the VT monitored through an external pneumotachograph. Ten breaths for each condition were compared for every tested situation. RESULTS: All tested ventilators underestimated VT (ranges of −21.7 mL to −83.5 mL, which corresponded to −3.6% to −14.7% of the externally measured VT). A direct relationship between leak and underestimation was found in 4 ventilators, with higher underestimations of the VT when the leakage increased, ranging between −2.27% and −5.42% for each 10 L/min increase in the leakage. A ventilator that included an algorithm that computes the pressure loss through the tube as a function of the flow exiting the ventilator had the minimal effect of leaks on the estimation of VT (0.3%). In 3 ventilators the underestimation was also influenced by mechanical pattern (lower underestimation with restrictive, and higher with obstructive). CONCLUSIONS: The inclusion of algorithms that calculate the pressure loss as a function of the flow exiting the ventilator in commercial models may increase the reliability of VT estimation.