TY - JOUR T1 - Cough Peak Flow Assessment Without Disconnection From the ICU Ventilator in Mechanically Ventilated Patients JF - Respiratory Care DO - 10.4187/respcare.10412 SP - respcare.10412 AU - Guillaume Fossat AU - Emmanuelle Desmalles AU - Léa Courtes AU - Cécile Fossat AU - Thierry Boulain Y1 - 2023/03/06 UR - http://rc.rcjournal.com/content/early/2023/03/06/respcare.10412.abstract N2 - BACKGROUND: Because ICU ventilators incorporate flow velocity measurement, cough peak expiratory flow (CPF) can be assessed without disconnecting the patient from the ICU ventilator. Our goal was to estimate the correlation between CPF obtained with the built-in ventilator flow meter (ventilator CPF) and CPF obtained with an electronic portable handheld peak flow meter connected to the endotracheal tube.METHODS: Cooperative mechanically ventilated patients who entered the weaning process and who were ventilated with pressure support < 15 cm H2O and PEEP < 9 cm H2O were eligible for the study. Their CPF measurements obtained on the extubation day were kept for analysis.RESULTS: We analyzed CPF obtained in 61 subjects. The mean ± SD value of ventilator CPF and peak flow meter CPF were 72.6 ± 27.5 L/min and 31.1 ± 13.4 L/min. The Pearson correlation coefficient was 0.63 (95% CI 0.45–0.76), P < .001. The ventilator CPF had an area under the receiver operating characteristic curve of 0.84 (95% CI 0.75–0.93) to predict a peak flow meter CPF < 35 L/min. Neither ventilator CPF nor peak flow meter CPF differed significantly between subjects who were or were not re-intubated within 72 h (n = 5) and failed to predict re-intubation at 72 h (area under the receiver operating characteristic curve of 0.64 [95% CI 0.46–0.82] and 0.47 [95% CI 0.22–0.74]).CONCLUSIONS: CPF measurements using a built-in ventilator flow meter were feasible in routine practice with cooperative ICU subjects who were intubated and correlated with CPF assessed by an electronic portable peak flow meter. ER -