TY - JOUR T1 - <span hwp:id="article-title-1" class="article-title">Sedation and Paralysis</span><span hwp:id="article-title-107" class="sub-article-title">Discussion</span> JF - Respiratory Care SP - 1024 LP - 1037 DO - 10.4187/respcare.02232 VL - 58 IS - 6 AU - Annop Piriyapatsom AU - Edward A Bittner AU - Jessica Hines AU - Ulrich H Schmidt Y1 - 2013/06/01 UR - http://rc.rcjournal.com/content/58/6/1024.abstract N2 - Sedation is used almost universally in the care of critically ill patients, especially in those who require mechanical ventilatory support or other life-saving invasive procedures. This review will focus on the sedation strategies for critically ill patients and the pharmacology of commonly used sedative agents. The role of neuromuscular blocking agents in the ICU will be examined and the pharmacology of commonly used agents is reviewed. Finally a strategy for rational use of these sedative and neuromuscular blocking agents in critically ill patients will be proposed. Discussion ER -