RT Journal Article SR Electronic T1 Approach to the Physiologically Challenging Endotracheal Intubation in the Intensive Care Unit JF Respiratory Care FD American Association for Respiratory Care SP respcare.10821 DO 10.4187/respcare.10821 A1 Andrew J Hickey A1 Matthew J Cummings A1 Briana Short A1 Daniel Brodie A1 Oliver Panzer A1 Purnema Madahar A1 Max R O’Donnell YR 2023 UL http://rc.rcjournal.com/content/early/2023/05/23/respcare.10821.abstract AB Endotracheal intubation for airway management is a common procedure in the ICU. Intubation may be difficult due to anatomic airway abnormalities but also due to physiologic derangements that predispose patients to cardiovascular collapse during the procedure. Results of studies demonstrate a high incidence of morbidity and mortality associated with airway management in the ICU. To reduce the likelihood of complications, medical teams must be well versed in the general principles of intubation and be prepared to manage physiologic derangements while securing the airway. In this review, we present relevant literature on the approach to endotracheal intubation in the ICU and provide pragmatic recommendations relevant to medical teams performing intubations in patients who are physiologically unstable.