TY - JOUR T1 - Severe Excessive Dynamic Airway Collapse in a Patient With Primary Sjögren's Syndrome JF - Respiratory Care SP - e156 LP - e159 DO - 10.4187/respcare.02929 VL - 59 IS - 10 AU - Sophie Ismael AU - Delphine Wermert AU - Kim-Diep Dang-Tran AU - Marion Venot AU - Jean-Yves Fagon AU - Jean-Luc Diehl Y1 - 2014/10/01 UR - http://rc.rcjournal.com/content/59/10/e156.abstract N2 - Airway and cystic lung diseases can be observed in patients with Sjögren's syndrome. We report a case of such a patient suffering from respiratory failure due to recurrent episodes of right pneumothorax, requiring invasive mechanical ventilation. Despite thoracic drainage and adequate pneumothorax management, the patient could not be weaned from the ventilator. Fiberoptic bronchoscopy revealed severe central excessive dynamic airway collapse of the lower part of the trachea and proximal bronchi. The severity of airway collapse was maximal at the intermediate bronchus level, with a near-complete obstruction during expiration. Inspiratory and expiratory computed tomography studies confirmed the fiberoptic findings and suggested a possible expiratory posterior compression of the intermediate bronchus by parenchymal lung cysts. Stenting was considered, but the patient died from ventilator-associated pneumonia before the procedure could be performed. This case is the first description of severe central excessive dynamic airway collapse in a patient with primary Sjögren's syndrome complicated by diffuse airway and cystic lung disease. ER -