%0 Journal Article %A John D Davies %A Mourad H Senussi %A Eduardo Mireles-Cabodevila %T Should A Tidal Volume of 6 mL/kg Be Used in All Patients? %D 2016 %R 10.4187/respcare.04651 %J Respiratory Care %P 774-790 %V 61 %N 6 %X It has been shown that mechanical ventilation by itself can cause lung injury and affect outcomes. Ventilator-induced lung injury is associated with high tidal volumes in lungs afflicted with ARDS. However, the question is: Do high tidal volumes have this same effect in normal lungs or lungs that have respiratory compromise stemming from something other than ARDS? Many clinicians believe that a tidal volume strategy of 6 mL/kg predicted body weight should be standard practice in all patients receiving mechanical ventilation. There is a growing body of evidence related to this issue, and this is the debate that will be tackled in this paper from both pro and con perspectives. %U https://rc.rcjournal.com/content/respcare/61/6/774.full.pdf