PT - JOURNAL ARTICLE AU - John D Davies AU - Mourad H Senussi AU - Eduardo Mireles-Cabodevila TI - Should A Tidal Volume of 6 mL/kg Be Used in All Patients? AID - 10.4187/respcare.04651 DP - 2016 Jun 01 TA - Respiratory Care PG - 774--790 VI - 61 IP - 6 4099 - http://rc.rcjournal.com/content/61/6/774.short 4100 - http://rc.rcjournal.com/content/61/6/774.full AB - It has been shown that mechanical ventilation by itself can cause lung injury and affect outcomes. Ventilator-induced lung injury is associated with high tidal volumes in lungs afflicted with ARDS. However, the question is: Do high tidal volumes have this same effect in normal lungs or lungs that have respiratory compromise stemming from something other than ARDS? Many clinicians believe that a tidal volume strategy of 6 mL/kg predicted body weight should be standard practice in all patients receiving mechanical ventilation. There is a growing body of evidence related to this issue, and this is the debate that will be tackled in this paper from both pro and con perspectives.