TY - JOUR T1 - Risk Factors for Pediatric Intensive Care Admission in Children With Acute Asthma JF - Respiratory Care SP - 1391 LP - 1397 DO - 10.4187/respcare.01325 VL - 57 IS - 9 AU - Gerbrich E van den Bosch AU - Peter JFM Merkus AU - Corinne MP Buysse AU - Annemie LM Boehmer AU - Anja APH Vaessen-Verberne AU - Leonieke N van Veen AU - Wim CJ Hop AU - Matthijs de Hoog Y1 - 2012/09/01 UR - http://rc.rcjournal.com/content/57/9/1391.abstract N2 - INTRODUCTION: Severe acute asthma in children is associated with substantial morbidity and may require pediatric ICU (PICU) admission. The aim of the study was to determine risk factors for PICU admission. METHODS: The study used a retrospective multicenter case-control design. The cases included children admitted to the PICU because of severe acute asthma and a history of out-patient treatment by pediatricians or pediatric pulmonologists. Controls were children with asthma without a PICU admission for severe acute asthma. The children were matched for sex, age, hospital, and time elapsed since the diagnosis of asthma. Fourteen possible risk factors were analyzed. RESULTS: Sixty-six cases were matched to 164 controls. In univariate analysis, all but one of the analyzed variables were significantly associated with PICU-hospitalization. After multivariate conditional logistic regression analysis, 4 risk factors remained significant. These included active or passive smoking, allergies, earlier hospitalization for asthma, and non-sanitized home. CONCLUSIONS: Physicians and parents should be aware of these risk factors, and efforts should be made to counteract them. ER -