RT Journal Article
SR Electronic
T1 Pulmonary Cryptococcus Infection After Mono-Chemotherapy With Gemcitabine
JF Respiratory Care
FD American Association for Respiratory Care
SP 339
OP 341
DO 10.4187/respcare.00652
VO 56
IS 3
A1 Yu-Guang Chen
A1 Te-Yu Lin
A1 Gen-Min Lin
A1 Jung-Chung Lin
YR 2011
UL http://rc.rcjournal.com/content/56/3/339.abstract
AB Mono-chemotherapy with gemcitabine (difluorodeoxycytidine) is an effective cancer chemotherapy, and is often used instead of a more effective but more toxic combination chemotherapy regimen. Infection associated with gemcitabine is very rare. We present a case of Cryptococcus neoformans pneumonia that developed after 5 courses of gemcitabine for advanced bladder carcinoma. Lung biopsy and antigens demonstrated C. neoformans. The pneumonia resolved after antifungal therapy.