@article {Duarte623, author = {Alexander G Duarte}, title = {Inhaled Bronchodilator Administration During Mechanical Ventilation}, volume = {49}, number = {6}, pages = {623--634}, year = {2004}, publisher = {Respiratory Care}, abstract = {Inhaled bronchodilators are routinely administered to mechanically ventilated patients to relieve dyspnea and reverse bronchoconstriction. A lower percentage of the nominal dose reaches the lower respiratory tract in a mechanically ventilated patient than in a nonintubated subject, but attention to device selection, administration technique, dosing, and patient-ventilator interface can increase lower-respiratory-tract deposition in a mechanically ventilated patient. Assessing the airway response to bronchodilator by measuring airway resistance and intrinsic positive end-expiratory pressure helps guide dosing and timing of drug delivery. Selecting the optimal aerosol-generating device for a mechanically ventilated patient requires consideration of the ease, reliability, efficacy, safety, and cost of administration. With careful attention to administration technique, bronchodilator via metered-dose inhaler or nebulizer can be safe and effective with mechanically ventilated patients.}, issn = {0020-1324}, URL = {https://rc.rcjournal.com/content/49/6/623}, eprint = {https://rc.rcjournal.com/content/49/6/623.full.pdf}, journal = {Respiratory Care} }