Results of aerosol delivery via HFNC with different models and mouth status

Mouth status	Flow setting(L/min)	Inhaled dose with 2 model, %		P
		NMT model	Adult manikin
Closed	15	24.7 ± 0.4	18.9 ± 1.4	<0.001
	45	6.5 ± 0.9	5.2 ± 0.8	0.038
Open	15	21.1 ± 0.6	24.4 ± 1.3	0.001
	45	7.7 ± 1.0	6.1 ± 0.5	0.013
P	15	0.0079	0.0079
	45	0.087	0.0952