Summary
Pulmonary alveolar proteinosis (PAP), in addition to acute generalized histoplasmosis, was found at autopsy of three adult males, 23, 51, and 52 years of age. All three patients became ill in the same region of Venezuela, south of Lake Maracaibo, an area considered highly endemic for histoplasmosis. The PAP may be due to an environmental factor.
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Angulo, O. A., Rodríguez, C.: Proteinosis alveolar pulmonar. Rev. Tisiol. Neumonol. 3, 11–33 (1962)
Rosen, S. A., Castleman, B., Liebow, A. A.: Pulmonary alveolar proteinosis. New Engl. J. Med. 258, 1123–1142 (1958)
Salfelder, K.: Zur Differentialdiagnose der Histoplasmose. Z. Tropenmed. Parasit. 11, 453–468 (1960)
Salfelder, K., Brass, K., Doehnert, G., Doehnert, R., Sauerteig, E.: Fatal disseminated histoplasmosis. Anatomic study of autopsy cases. Virchows Arch. Abt. A 350, 303–335 (1970)
Sunderland, W. A., Campbell, R. A., Edwards, M. J.: Pulmonary alveolar proteinosis and pulmonary cryptococcosis in an adolescent boy. J. Pediat. 80, 450–456 (1972)
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This work was supported in part by the CONICIT (Consejo Nacional de Investigaciones Científicas y Tecnológicas), Caracas and the Consejo de Desarrollo Científico y Humanístico de la ULA, Mérida, Venezuela, South América.
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Hartung, M., Salfelder, K. Pulmonary alveolar proteinosis and histoplasmosis. Virchows Arch. A Path. Anat. and Histol. 368, 281–287 (1975). https://doi.org/10.1007/BF00432306
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DOI: https://doi.org/10.1007/BF00432306