Abstract
We studied airway occlusion pressure (P 0.1) and maximal inspiratory pressure (PIMax) in 10 healthy volunteers (Group A), 10 early postsurgical cardiac patients on spontaneous breathing (Group B), 10 patients mechanically ventilated for ARF (Group C), 10 patients weaning from mechanical ventilation after ARF (Group D) and 10 patients extubated after post-ARF (Group E). We calculated the index P 0.1/PIMax in an attempt to link the ventilatory demands and muscle ventilatory reserve. We found that the sensitivity and specificity in diagnosing the need for either full (C), partial (D) or no ventilatory support (A, B, E) by means of the P 0.1 were C=(50%, 95%), D=(70%, 72%) and A+B+E=(83%, 90%) respectively. When the index P 0.1/PIMax was used they were C=(90%, 100%), D=(80%, 87%) and A+B+E=(86%, 90%). We conclude that the index P 0.1/PIMax increases the reliability of P 0.1 alone to correctly classify the patients that will need either full, partial or no ventilatory support in ARF.
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References
Marini J (1986) The physiologic determinants of ventilator dependence. Respir Care 31:271–282
Whitelaw W, Derenne JPh, Milic-Emili J (1975) Occlusion pressure as a measure of respiratory center output in conscious man. Respir Physiol 23:181–199
Aubier M, Murciano D, Fournier M, Milic-Emili J, Pariente R, Derenne JPh (1980) Central respiratory drive in acute respiratory failure of patients with obstructive pulmonary disease. Am Rev Respir Dis 122:191–199
Milic-Emili J (1982) Recent advances in clinical assessment of control of breathing. Lung 160:1–17
Marini J, Smith Th, Lamb V (1986) Estimation of inspiratory muscle strength in mechanically ventilated patients: the measurement of maximal inspiratory pressure. J Crit Care 1:32–38
Fleury B, Murciano D, Talamo C, Aubier M, Pariente R, Milic-Emili J (1985) Work of breathing in patients with chronic obstructive pulmonary disease in acute respiratory failure. Am Rev Respir Dis 131:822–827
Gallager C, Hof V, Younes M (1985) Effect of inspiratory muscle fatigue on breathing pattern. J Appl Physiol 59:1152–1158
Hussain S, Pardy R, Dempsey J (1985) Mechanical impedance as determinant of inspiratory neural drive during exercise in humans. J Appl Physiol 59:365–375
Montgomery A, Holle R, Neagley S, Pierson D, Schoene R (1987) Prediction of successful ventilator weaning using airway occlusion pressure and hypercapnic challenge. Chest 91:496–499
Murciano D, boczkowski J, Lecocguic Y, Milic-Emili J, Pariente R, Aubier M (1988) Tracheal occlusion pressure: a simple index to monitor respiratory muscle fatigue during acute respiratory failure in patients with COPD. Ann Intern Med 108:800–805
Sassoon C, Te T, Mahutte C, Light R (1987) Airway occlusion pressure. An important indicator for successful weaning in patients with chronic obstructive pulmonary disease. Am Rev Respir Dis 135:107–113
Murciano D, Aubier M, Bussi S, Derenne JPh, Pariente R, Milic-Emili J (1982) Comparison of esophageal, tracheal and mouth occlusion pressure in patients with chronic obstructive pulmonary disease during acute respiratory failure. Am Rev Respir Dis 126:837–841
Tobin M (1988) Respiratory monitoring in the intensive care unit. Am Rev Respir Dis 138:1625–1642
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Fernández, R., Cabrera, J., Calaf, N. et al. P0.1/PIMax: An index for assessing respiratory capacity in acute respiratory failure. Intensive Care Med 16, 175–179 (1990). https://doi.org/10.1007/BF01724798
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DOI: https://doi.org/10.1007/BF01724798