Case reportSecondary pulmonary alveolar proteinosis occurring in two patients with acquired immune deficiency syndrome
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Cited by (76)
Pulmonary Alveolar Proteinosis Syndrome
2015, Murray and Nadel's Textbook of Respiratory Medicine: Volume 1,2, Sixth EditionPulmonary alveolar proteinosis and superinfection with pulmonary tuberculosis in a case
2012, Respiratory Medicine Case ReportsCitation Excerpt :Two forms are described: primary or idiopathic, which occurs in the absence of another illness or a known environmental exposure; and secondary, when associated with another morbid condition, especially infectious or neoplastic, in various states of immunosuppression, as well as in those resulting from the inhalation of chemical agents and mineral particles (silica, aluminum, titanium, and some insecticides). Several etiological agents have been identified in this population: Aspergillus sp., Nocardia sp., Mycobacterium sp., Cryptococcus neoformans, Histoplasma capsulatum, Pneumocystis carinii, and virus.2,3 The association of alveolar proteinosis and pulmonary tuberculosis has been rarely reported.
The molecular basis of pulmonary alveolar proteinosis
2010, Clinical ImmunologyCitation Excerpt :The diagnosis is usually made based on the presence of typical radiological manifestations and lung histopathological findings. Secondary PAP has been reported in association with various diverse clinical disorders, including hematological disorders (myelodysplastic syndrome, leukemia, lymphoma, aplastic anemia, pharmacologically induced leukopenia, and others), immunological diseases (severe combined immunodeficiency, monoclonal gammopathy, selective immunoglobulin A deficiency, and others), lysinuric protein intolerance, and infections (Cytomegalovirus, M. tuberculosis, Nocardia, Pneumocystis jiroveci, and others) [34,62–80]. It has also been reported in association with various toxic inhalation syndromes, including inhalation of inorganic dusts (silica, cement, titanium, and aluminum), organic dusts (sawdust, fertilizer, bakery flour, and others), and fumes (chlorine, varnish, and others) [81–88].
Pulmonary Manifestations of Hematologic and Oncologic Diseases
2009, Pulmonary Manifestations of Pediatric DiseasesAutoimmune Pulmonary Alveolar Proteinosis
2022, American Journal of Respiratory and Critical Care Medicine