An assessment of central-peripheral ventilatory chemoreflex interaction in humans
References (25)
- et al.
Carbon dioxide versus H ion as a chemoreceptor stimulus
Brain Res.
(1982) - et al.
The transient respiratory effects in man of sudden changes in alveolar CO2 in hypoxia in high oxygen
Respir. Physiol.
(1974) - et al.
Changes in arterial plasma potassium and ventilation during exercise in man
Respir. Physiol.
(1989) - et al.
Effects of respiratory and (isocapnic) metabolic arterial acid-base disturbances on medullary extracellular fluid pH and ventilation in cats
Respir. Physiol.
(1983) - et al.
Influence of peripheral O2 tension on the ventilatory response to CO2 in cats
Respir. Physiol.
(1983) - et al.
Central and peripheral chemoreflex loop gain in normal and carotid body-resected subjects
J. Appl. Physiol.
(1979) - et al.
Effects of potassium, oxygen and carbon dioxide on the steady-state discharge of cat carotid body chemoreceptors
J. Physiol. (London)
(1988) - et al.
The effect of intravenous infusion of noradrenaline on the respiratory response to carbon dioxide in man
Quart. J. Exp. Physiol.
(1958) - et al.
Integration of respiratory responses to changes in alveolar partial pressures of CO2 and O2 and in arterial pH
The ventilatory response to carbon dioxide and oxygen in man
The influence of oxygen on the ventilatory response to carbon dioxide in man
J. Physiol. (London)
The peripheral chemoreceptor threshold to carbon dioxide in man
J. Physiol. (London)
Cited by (35)
Short-term modulation of the ventilatory response to exercise is preserved in obstructive sleep apnea
2017, Respiratory Physiology and NeurobiologyHypercapnia attenuates inspiratory amplitude and expiratory time responsiveness to hypoxia in vagotomized and vagal-intact rats
2012, Respiratory Physiology and NeurobiologyCitation Excerpt :Central and peripheral chemoreceptor influences on breathing are traditionally modeled as additive for simplicity although many extant data in human subjects and animal models suggest the possibility of not only additive (Clement et al., 1992, 1995; Heeringa et al., 1979; Mohan and Duffin, 1997; StCroix et al., 1996; Swanson and Bellville, 1974; van Beek et al., 1983) but also hyperadditive (Adams et al., 1978; Cunningham et al., 1986; da Silva et al., 2011; Honda et al., 1981; Loeschcke et al., 1963; Robbins, 1988; Roberts et al., 1995; Tenney and Brooks, 1966; Teppema et al., 2010) or even hypoadditive interaction (Adams and Severns, 1982; Berger et al., 1978; Cragg and Drysdale, 1983; Eldridge et al., 1981; Gesell et al., 1940; Giese et al., 1978; Ou et al., 1976; Smith et al., 1984).
Central-peripheral respiratory chemoreflex interaction in humans
2012, Respiratory Physiology and NeurobiologyCitation Excerpt :Using temporal separation experiments in humans initially found evidence for a positive interaction (Robbins, 1988). Later experiments from the same laboratory found the interaction to be additive (Clement et al., 1992) and were later confirmed (St. Croix et al., 1996). With the recent increase in interest in central–peripheral interaction (Smith et al., 2010) in mind we designed experiments to test for interaction based on a temporal separation that differed from past protocols.
An interdependent model of central/peripheral chemoreception: Evidence and implications for ventilatory control
2010, Respiratory Physiology and NeurobiologyAre the carotid bodies of the guinea-pig functional?
2007, Comparative Biochemistry and Physiology - A Molecular and Integrative PhysiologyA test of the interaction between central and peripheral respiratory chemoreflexes in humans
2023, Journal of Physiology