ORIGINAL ARTICLES: GENERAL THORACICPrimary non-Hodgkin’s lymphoma of the lung
Section snippets
Material and methods
From 1975 to 1995, 189 patients with a diagnosis of lymphoma underwent a thoracic procedure at the Mayo Clinic. Forty-eight of these patients were found to have primary non-Hodgkin’s lymphoma of the lung. The following were used to identify them: involvement of the lung with non-Hodgkin’s lymphoma; no past history of lymphoma; no evidence of extrathoracic disease at the time of diagnosis including negative results of abdominal computed tomographic scanning and bone marrow biopsy; and no
Results
Complete surgical resection with negative margins was possible in 19 patients (40%). In the remaining 29 patients, the surgical procedure was an incomplete resection (21 patients with bilateral disease, 8 patients with extensive local disease that was unresectable). There were no operative deaths. Complications occurred in 18 patients (37.5%) and included cardiac dysrhythmia in 5, prolonged air leak in 5, hemorrhage requiring reexploration in 3, atelectasis requiring bronchoscopy in 2, and
Comment
The lung is a frequent site of secondary involvement by Hodgkin’s and non-Hodgkin’s lymphoma. However, primary lymphoid tumors of the lung are rare. There is confusion about the definition and classification of these tumors despite the comprehensive review by Saltzstein [7] in 1963. Diseases that have reactive lymphoid proliferations such as pseudolymphoma, lymphoid interstitial pneumonitis, lymphomatoid granulomatosis, and follicular bronchiolitis are morphologically difficult to distinguish
References (23)
- et al.
Regression of primary gastric lymphoma of mucosa-associated lymphoid tissue type after cure of Helicobacter pylori infection. MALT Lymphoma Study Group
Lancet
(1995) - et al.
Regression of primary low-grade B-cell gastric lymphoma of mucosa-associated lymphoid tissue type after eradication of Helicobacter pylori
Lancet
(1993) - et al.
Pulmonary lymphomascurrent concepts
Hum Pathol
(1983) - et al.
A revised European-American classification of lymphoid neoplasmsa proposal from the International Lymphoma Study Group
Blood
(1994) - et al.
Primary non-Hodgkin’s lymphoma and pseudolymphoma of lunga study of 161 patients
Hum Pathol
(1983) - et al.
Primary pulmonary lymphomas. A clinical study of 70 cases in nonimmunocompromised patients
Chest
(1993) - et al.
Detection of pulmonary lymphoma by bronchoalveolar lavage
Chest
(1987) - et al.
Primary pulmonary lymphoma
Lung Cancer
(1992) - et al.
A clinical analysis of two indolent lymphoma entitiesmantle cell lymphoma and marginal zone lymphoma (including the mucosa-associated lymphoid tissue and monocytoid B-cell subcategories): a Southwest Oncology Group study
Blood
(1995) - et al.
Bronchial lymphoid tissue
Lab Invest
(1973)
Reactive pulmonary lymphoid disorders
Histopathology
Cited by (211)
Pulmonary mucosa-associated lymphoid tissue lymphoma forming a reversed halo sign from ground-glass opacity
2023, Radiology Case ReportsImaging of the rare cystic lung diseases
2022, Current Problems in Diagnostic RadiologyDeciphering the genetic landscape of pulmonary lymphomas
2021, Modern PathologyMaltoma veiled in the lung-a rare case of pulmonary and gastric maltoma
2021, Respiratory Medicine Case Reports