Original articleCardiovascularInfluence of Pleurotomy on Pulmonary Function After Off-Pump Coronary Artery Bypass Grafting
Section snippets
Patients and Methods
This study was performed in the Pirajussara and Sao Paulo Hospitals of the Federal University of Sao Paulo, Sao Paulo, Brazil. The Institutional Ethics Committee for Clinical Research approved the protocol, and written informed consent was obtained from all participants of the study.
Results
Preoperative and intraoperative patient characteristics are summarized in Table 1. No statistical difference was found in terms of age, gender, body mass index (BMI), preoperative pulmonary function, operative time, and number of grafts per patient.
A significant decrease in pulmonary function tests was observed in both groups until POD 5 (p < 0.05). The FVC mean, expressed as a percentage of the preoperative value, was significantly lower in the OP group than in the IP group on PODs 1 (33.3% ±
Comment
The present study demonstrates that an evident impairment of pulmonary function occurs in the early postoperative period of off-pump CABG independent of the pleurotomy, an effect already reported by other authors studying the same subject in on-pump CABG [3, 4, 5, 6, 17, 18]. The cause of the significant reduction on pulmonary function after CABG surgery is multifactorial [10]:
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The general anesthesia results in reduction of the diaphragmatic tonus with an upward shift, relaxation of the chest
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