Elsevier

Respiratory Medicine

Volume 98, Issue 10, October 2004, Pages 938-944
Respiratory Medicine

Comparison of four demand oxygen delivery systems at rest and during exercise for chronic obstructive pulmonary disease

https://doi.org/10.1016/j.rmed.2004.03.010Get rights and content
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Abstract

Objectives: The aim of this study was to assess the performance of four demand oxygen delivery systems (DODS) in improving oxygenation and effort tolerance, at rest and during exercise, in chronic obstructive pulmonary disease (COPD) patients.

Materials and methods: Thirteen COPD patients were prospectively included. Four DODS (Oxiclip, Versatile, Venture and Impulse) were compared with continuous-flow oxygen (CFO).Nine of these patients performed 6-min walking tests on room air and on 3 l/min oxygen by DODS and CFO; Oxygen saturation, walking distance and the Borg dyspnea score were recorded.

Results: With all four DODS devices arterial oxygenation was improved with lower oxygen flow rates than with CFO. Oxygen economy was best with Impulse, but at a cost of less satisfactory oxygenation. Exercise desaturation was similar with CFO, Oxiclip, Venture, and Impulse but significantly higher with Versatile (P<0.05). Borg dyspnea scores were similar with CFO, Oxiclip, Venture, and Versatile but worse with Impulse (P<0.05). There was no significant difference in walking distances.

Conclusions: All four DODS improved oxygen saturation and saved oxygen. However, performance was better with the two devices (Oxiclip and Venture) that deliver a bolus of oxygen at inspiration onset.

Keywords

Demand oxygen delivery system
Chronic obstructive pulmonary disease
Long-term oxygen therapy

Abbreviations

COPD
chronic obstructive pulmonary disease
DODS
demand oxygen delivery system
CFO
continuous flow oxygen
FEV1
forced expiratory volume in one second
TLC
total lung capacity
FVC
forced vital capacity
RR
respiratory rate
sd
standard deviation.

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This study was supported by an unrestricted educational grant from Air Liquide Santé.