Efficacy and safety of umeclidinium added to fluticasone furoate/vilanterol in chronic obstructive pulmonary disease: Results of two randomized studies
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Keywords
Long-acting muscarinic antagonist
Inhaled corticosteroid
Long-acting beta2 agonist
Bronchodilation
Abbreviations
AE
adverse event
ASE
all subjects enrolled
CAT
COPD Assessment Test
CI
confidence interval
COPD
chronic obstructive pulmonary disease
FEV1
forced expiratory volume in one second
FF
fluticasone furoate
FVC
forced vital capacity
GOLD
Global Initiative for Chronic Obstructive Lung Disease
HRQoL
health-related quality of life
ICS
inhaled corticosteroid
ITT
intent-to-treat
LABA
long-acting beta2 agonist
LAMA
Long-acting muscarinic antagonist
LS
least squares
MedDRA
Medical Dictionary for Regulatory Activities
PBO
placebo
PRO
patient-reported outcome
QoL
quality of life
RI
run-in
SAE
serious adverse event
SGRQ
St George's Respiratory Questionnaire
UMEC
umeclidinium
VI
vilanterol
WM
weighted mean
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Copyright © 2015 The Authors. Published by Elsevier Ltd.