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High-flow nasal cannula and extubation success in the premature infant: a comparison of two modalities

Journal of Perinatology volume 30, pages 805–808 (2010)Cite this article

Subjects

Abstract

Objective:

To compare the effectiveness of Fisher and Paykel (FP) and Vapotherm (VT) high-flow nasal cannula (HFNC) in preventing reintubation either within 72 h or <7 days after extubation of premature infants. The primary outcome was the rate of extubation failure defined as reintubation within 72 h. Secondary outcomes included reintubation after ⩽7 days.

Study Design:

This was a prospective, randomized pilot study comparing the extubation success of 40 infants born between 26 and 29 weeks of gestation.

Result:

The rate of extubation failure at 72 h was 18% for FP and 9% for VT. The failure rate ⩽7 days after extubation was 30% for FP and 27% for VT. None of these differences were statistically significant.

Conclusion:

There was no difference between FP and VT in the extubation success of infants born between 26 and 29 weeks.

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Acknowledgements

We acknowledge Fisher & Paykel Healthcare and Vapotherm for funding this study. We also wish to thank the Crouse Hospital NICU nurses, respiratory therapists and staff for supporting this study. Special thanks to Lisa Smith, PNP, for her work as a research nurse.

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Authors and Affiliations

  1. Division of Newborn Medicine, Weill Cornell Medical College, New York, NY, USA

    S M Miller

  2. Neonatal Associates of Central New York, Crouse Hospital, Syracuse, NY, USA

    S A Dowd

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  1. S M Miller
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  2. S A Dowd
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Correspondence to S M Miller.

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Competing interests

Fisher & Paykel Healthcare and Vapotherm jointly funded this study. We have not received a salary or other personal benefits, and do not hold stock in either company. The study was designed, conducted and analyzed separately from Fisher & Paykel Healthcare and Vapotherm.

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Miller, S., Dowd, S. High-flow nasal cannula and extubation success in the premature infant: a comparison of two modalities. J Perinatol 30, 805–808 (2010). https://doi.org/10.1038/jp.2010.38

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