SERIES : RARE CHRONIC DISEASESurfactant proteins: role in lung physiology and disease in early life
References (65)
- et al.
Diagnosis of respiratory distress syndrome by amniocentesis
Am J Obstet Gynecol
(1971) - et al.
Assignment of the human pulmonary surfactant protein D gene (8FTP4) to 10q22–q23 close to the surfactant protein A gene cluster
Genomics
(1993) - et al.
Proteolipid in bovine lung surfactant: its role in surfactant function
Biochem Biophys Res Commun
(1986) - et al.
Pulmonary surfactant protein SP-C causes packing rearrangements of dipalmitoyl phosphotidylcholine in spread monolayers
Biophys J
(1992) - et al.
Genomic organization of human surfactant protein D: SP-D is encoded on chromosome 10q22.2–23.1
J Biol Chem
(1993) - et al.
Artificial surfactant therapy in hyaline membrane disease
Lancet
(1980) - et al.
Molecular and phenotypic vairability in the congenital alveolar proteinosis associated with surfactant protein B deficiency
J Pediatr
(1994) - et al.
Lung transplantation for treatment of infants with surfactant protein B deficiency
J Pediatr
(1997) - et al.
Surfactant protein B deficiency: antenatal diagnosis and prospective treatment with surfactant replacement
J Pediatr
(1994) - et al.
Defective expression of granulocyte-mcarophage colony-stimulating factor/interleukin-3/interleukin-5 receptor common beta chain in children with acute myeloid leukemia associated with respiratory failure
Blood
(1998)
Pulmonary alveolar proteinosis is a disease of decreased availability of GM-CSF rather than an intrinsic cellular defect
Clin Immunol
Acute effects of a single dose of porcine surfactant on patients with adult respiratory distress syndrome
Chest
Function and composition of pulmonary surfactant and surfactant-derived fatty acid profiles are altered in young adults with CF
Chest
Neue auffassungen uber einem Grund-befriff der Atemechanik
Gesamte Exp Med
Properties, function and origin of alveolar lining layer
Nature
Surface tension of lung extracts
Proc Soc Exp Biol Med
Surface properties in relation to atelectasis and hyaline membrane disease
Am J Dis Child
Composition of surface-active material isolated from beef lung
Proc Natl Acad Sci USA
The biochemical development of surface activity in mammalian lung. I. The surface-active phospholipids: the separation and distribution of surface-active lecithin in the lung of the developing rabbit fetus
Pediatr Res
Isolation of apoproteins from canine surface active material
Am J Physiol
Deficiency of surfactant protein B in congenital alveolar proteinosis
N Eng J Med
The pulmonary surfactant system: biochemical and clinical aspects
Lung
Immunomodulatory functions of surfactant
Physiol Rev
Regulation of pulmonary surfactant secretion and clearance
Annu Rev Physiol
Regulation of lung surfactant protein secretion
Am J Physiol
The absence of phosphatidylglycerol in surfactant
Pediatr Res
A proposed nomenclature of pulmonary surfactant-associated proteins
Am Rev Respir Dis
Purification and biochemical characterization of CP-4 (SP-D): a collagenous surfactant-associated protein
Biochemistry
Surfactant protein A is localized at the corners of the pulmonary tubular myelin lattice
J Histochem Cytochem
Surfactant proteins A and D increase in response to intratracheal lipopolysaccharide
Am J Respir Cell Mol Biol
Biphasic glucocorticoid regulation of surfactant protein-A: characterization of the inhibitory process
Am J Physiol
Interferon-gamma and synthesis of surfactant components by cultured human fetal lung
Am J Respir Cell Mol Biol
Cited by (21)
A homotetrameric hemoglobin expressed in alveolar epithelial cells increases blood oxygenation in high-altitude plateau pika (Ochotona curzoniae)
2022, Cell ReportsCitation Excerpt :We verified that δ was expressed in ATI cells, ATII cells, and LBs of plateau pikas. In vivo, ATI cells comprise much of the surface area of the alveolar epithelium and function in gas exchange (Williams, 2003; Bishop, 2004), whereas ATII cells are the primary producers of PS, which is essential for normal lung function and innate immunity (Mallory, 2001; Poynter and LeVine, 2003; Wright, 2003). Using TEM, we clearly observed the ATII cells of plateau pikas and structurally intact LBs, whereas ATI cells were without LBs.
Effect of pulmonary surfactant on the dispersion of carbon nanoparticles
2021, Colloids and Surfaces A: Physicochemical and Engineering AspectsCitation Excerpt :Evidence has shown that inhaled nanoparticles can penetrate deeply into the peripheral areas of the lungs, where they come into directly contact with the pulmonary surfactant (PS), which is distributed in the alveolar lining [8,9]. PS is a mixture comprising approximately 90% lipids [mainly dipalmitoylphosphatidylcholine (DPPC)] and 10% surfactant-associated proteins (SP-A, SP-B, SP-C and SP-D) [10–12]. It can form a liquid film at the air-water interface of the alveoli, and it can reduce surface tension to a near-zero value, thereby enabling the alveolar-capillary film to maintain a large surface area that facilitates respiration [13,14].
Time-dependent recruitment effects in ventilated healthy and lung-injured rats: " Recruitment-memory"
2012, Respiratory Physiology and NeurobiologyCitation Excerpt :Proteinous oedema, resulting from lung injury, furthermore leads to the inhibition of surfactant activity and as a consequence to lung collapse due to high surface tension. Since turnover time of surfactant is approximately 12 h or 10% per hour (Mallory, 2001), the experimental time would have been too short to allow surfactant to be rebuilt. Hypophase contains precursor material of surfactant from the type II pneumocytes and moves towards regions of high surface tension (Scarpelli, 1998), so in the healthy lungs there is some redistribution of surfactant.
Respiratory Disorders of the Newborn
2008, Pediatric Respiratory MedicineHemoglobin is expressed by alveolar epithelial cells
2006, Journal of Biological Chemistry