Chest
Selected ReportsTreatment of Diffuse Tracheomalacia Secondary to Relapsing Polychondritis With Continuous Positive Airway Pressure
Section snippets
Case Report
A 46-year-old woman was transferred to the Toronto Hospital for management of subglottic stenosis. She had been managed in the past for presumed asthma with bronchodilators and oral corticosteroids. She never smoked and had no occupational exposures. Six months prior to admission she developed increasing paroxysms of breathlessness and cough. Her activities of daily living were becoming increasingly limited owing to persistent dyspnea, and she eventually became completely bedridden. There was
Discussion
Patients with RP typically present with auricular chondritis, inflammatory arthritis, and nasal chondritis. Respiratory tract involvement in RP is an uncommon presenting feature, but its incidence increases as the disease progresses. Females develop airway complications more frequently.2, 3, 4 Patients who present with respiratory tract involvement have a worse prognosis than those with other organ involvement and have a poorer response to oral corticosteroids.2, 3, 5 The patient reported
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Cited by (83)
Interventionnal bronchoscopy for the treatment of tracheobronchomalacia
2023, Revue des Maladies RespiratoiresLong-Term Outcome of Metallic Stenting for Central Airway Involvement in Relapsing Polychondritis
2019, Annals of Thoracic SurgeryCitation Excerpt :As the first-line therapy, systematic treatment primarily relying on immunosuppressive agents is used to thwart the inflammatory destruction of cartilaginous structures, but with disappointing results [3, 15]. Noninvasive positive pressure ventilation was reported to achieve maintenance of adequate ventilation in sporadic cases with complete reversible airway collapse, but it interferes with the physical activity of patients [16, 17]. Moreover, tracheostomy and endotracheal tube insertion are likely to benefit only patients with subglottic involvement [18].
Tracheobronchomalacia and Excessive Dynamic Airway Collapse
2018, Clinics in Chest MedicineTracheobronchomalacia
2017, Disease-a-MonthRelapsing polychondritis: prevalence of cardiovascular diseases and its risk factors, and general disease features according to gender
2017, Revista Brasileira de ReumatologiaCentral Airway Obstruction: Benign Strictures, Tracheobronchomalacia, and Malignancy-related Obstruction
2016, ChestCitation Excerpt :TBM due to relapsing polychondritis is one such disease for which one or more stents are often necessary because of a diffuse lack of airway cartilaginous support (Fig 6). For EDAC, NIPPV can be offered with nocturnal and intermittent application during the day, with pressure settings determined during bronchoscopic titration (Fig 6).65-67 QOL and functional status are improved in the short term in 70% and dyspnea in 90% of patients after silicone stent insertion for ECAC.