Chest
Clinical Investigations in Critical CareClinical Course and Outcome of Patients Admitted to an ICU for Status Asthmaticus
Section snippets
Materials and Methods
The study involves prospectively collected data of 132 hospital admissions of 89 patients with status asthmaticus. The data were collected as part of the screening of patients admitted to our medical ICU (MICU) for severe exacerbation of asthma or chronic obstructive airway disease for a prospective, randomized study comparing permissive hypercapnia and conventional ventilation. This study included patients in all 132 hospital admissions who were consecutively treated in our MICU over the
Results
The age at first hospital admission, race, and sex of the 89 patients are listed in Table 1. During the 3-year study period, 1 patient was admitted to the MICU nine times, 1 patient was admitted seven times, 2 patients were admitted five times, 2 patients were admitted four times, 5 patients were admitted three times, 5 patients were admitted twice, and 73 patients were admitted once.
The age of the patients at admission to the MICU was 41.9 ± 15.0 years. Invasive mechanical ventilation was
Discussion
In this study, most of the 89 patients admitted to an MICU of an inner-city hospital for status asthmaticus were African American and female. Nonpulmonary organ failure and sepsis developed in patients in 12% and 13% of the 132 hospital admissions, respectively. The in-hospital mortality rate of 8% was higher than the mortality rate predicted by the APACHE II prognostic system. Although it did not reach statistical significance, none of the male patients died, compared with 11 of the 70 female
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