Chest
The Shape of the Maximum Expiratory Flow Volume Curve
Section snippets
METHODS
A cross-sectional study of the residents in three communities, Lebanon and Ansonia, Connecticut, and Winnsboro, South Carolina, was undertaken from 1972 to 1974. In each town, all persons ages seven years and older who lived in a geographically defined area were eligible to participate. Surveys were conducted in a standardized manner in a mobile van equipped with computer facilities for recording answers to a questionnaire on respiratory health, and for computing the results of pulmonary
RESULTS
Table 1 describes the distribution of the 2,382 males and 2,758 females in the study by age, by smoking status, by lung function pattern, and by presence of lung disease and symptoms.
Values for β ranged from 137.9 degrees to 255.8 degrees, with an overall mean value of 199.6 ± 18.9 (mean ± SD). Table 2 shows the mean β for the population by sex, age and smoking status. Controlling for age and cigarette smoking, females have a pattern of larger β angles than males. Controlling for sex and
DISCUSSION
We have shown for the first time that a simple parameter, angle P, related to the shape of the MEFV curve is useful in explaining previous characterizations of the shape of MEFV.
As with other lung function parameters, we have shown that β is different for men and women, with female subjects having larger mean values of β than male. This sex difference is not eliminated when controlling for other factors influencing β such as smoking history and age. Similarly, β is seen to change with age,
APPENDIX
The angle formed by connecting the projection of the peak flow point on the y-axis to the mid-flow point ( max50%) and that point to the residual volume point is designated β (Fig 1). The angles β? and β? as illustrated in the figure are related to β by the formula
The relationship between β? and flows measured on the MEFV curve is given by the formula
Similarly,
From (2) and (3) it follows that
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This study was supported by contract J-9-M-0168 from the US Department of Labor and Grant 5R01 HL 213512, NHL BI.
Manuscript received Jan~ 11; revision accepted March 8.