[The effect of endurance training on the neovascularization of skeletal musculature]

Acta Cir Bras. 2006 Nov-Dec;21(6):398-401. doi: 10.1590/s0102-86502006000600008.
[Article in Portuguese]

Abstract

Purpose: To quantify the capillaries in the skeletal muscular tissue of mice with induced peripheral arterial insufficiency, after endurance training.

Method: It was used Wistar mice in 70 days age range, subjected to the total occlusion of right femoral artery. The animals were divided into two groups: sedentary group (SG; n = 05), subjected to activities in the cage; and trained group (TG; n = 05), subjected to an endurance training in cycle ergometer twice a day 17m/min, by 5 minutes, 5 days per week during 10 weeks. The analysis was realized by the histologic observation of the vastus medialis muscle of injured member.

Results: The average number of capillaries in the muscular tissue was greater in TG (5,2 +/- 0,83) than in SG (1,6 +/- 1,14) (p < 0,05).

Conclusion: In animals with induction of peripheral arterial insufficiency, the endurance training provides a process of muscular adaptation which is observed by the increase in the number of capillaries of animals subjected to this kind of training.

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Capillaries
  • Male
  • Muscle, Skeletal / blood supply*
  • Neovascularization, Physiologic / physiology*
  • Physical Conditioning, Animal / physiology*
  • Physical Endurance / physiology*
  • Rats
  • Rats, Wistar
  • Time Factors