[Pulmonary tuberculosis: association between extent of the residual pulmonary lesion and alteration in the lung function]

Rev Assoc Med Bras (1992). 2008 Sep-Oct;54(5):406-10. doi: 10.1590/s0104-42302008000500012.
[Article in Portuguese]

Abstract

Objective: To describe alterations in spirometric variables and its disturbances and to study the existence of a relationship between extent of the residual lung lesion at the end of treatment for tuberculosis and alteration of the lung function measured by spirometry.

Methods: Analyzed were 96 patients with diagnosis of pulmonary tuberculosis, treated in three health centers in the metropolitan area of Recife, from January, 2003 to November, 2005. Patients of both genders, 15 years of age or older were included, whose chest x-rays at end of the treatment were classified according to criteria of the National Tuberculosis Association (NTA) for extent of lung lesion. Patients replied to a questionnaire at the beginning of the survey, and were submitted to spirometry after conclusion of treatment.

Results: Of the 96 patients, 89.6% presented with radiographic sequels. About 54% had moderate to severe sequels. These radiographic alterations correspond to 24.6% and 73.8% respectively of alterations in the pulmonary function.

Conclusion: The large number of residual radiographic lesionss (89.6%) and breathing dysfunction (66,7%) identified in this survey call attention to the fact that treatment of a patient with pulmonary tuberculosis must not be restricted to bacteriological healing of the disease. Identification of the residual lung lesions and of the breathing dysfunction in patients who conclude treatment will promote early actions to treat these sequels, improving the quality of life of these patients.

Publication types

  • Multicenter Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Alcohol Drinking / physiopathology
  • Brazil
  • Chi-Square Distribution
  • Comorbidity
  • Female
  • Humans
  • Lung / diagnostic imaging
  • Lung / physiopathology*
  • Lung Diseases, Obstructive / diagnostic imaging
  • Lung Diseases, Obstructive / etiology*
  • Lung Diseases, Obstructive / physiopathology
  • Male
  • Middle Aged
  • Radiography
  • Reference Values
  • Severity of Illness Index
  • Smoking / physiopathology
  • Spirometry
  • Tuberculosis, Pulmonary / complications*
  • Tuberculosis, Pulmonary / diagnostic imaging
  • Vital Capacity / physiology
  • Young Adult