Clinical, radiological and therapeutic characteristics of patients with COVID-19 in Saudi Arabia

PLoS One. 2020 Aug 6;15(8):e0237130. doi: 10.1371/journal.pone.0237130. eCollection 2020.

Abstract

Background: Coronavirus disease 2019 (COVID-19) is a rapidly spreading global pandemic. The clinical characteristics of COVID-19 have been reported; however, there is limited research investigating the clinical characteristics of COVID-19 in the Middle East. This study aims to investigate the clinical, radiological and therapeutic characteristics of patients diagnosed with COVID19 in Saudi Arabia.

Methods: This study is a retrospective single-centre case series study. We extracted data for patients who were admitted to the Al-Noor Specialist Hospital with a PCR confirming SARS-COV-2 between 12th and 31st of March 2020. Descriptive statistics were used to describe patients' characteristics. Continuous data were reported as mean ± SD. Chi-squared test/Fisher test were used as appropriate to compare proportions for categorical variables.

Results: A total of 150 patients were hospitalised for COVID-19 during the study period. The mean age was 46.1 years (SD: 15.3 years). The most common comorbidities were hypertension (28.8%, n = 42) and diabetes mellitus (26.0%, n = 38). Regarding the severity of the hospitalised patients, 105 patients (70.0%) were mild, 29 (19.3%) were moderate, and 16 patients (10.7%) were severe or required ICU care.

Conclusion: This case series provides clinical, radiological and therapeutic characteristics of hospitalised patients with confirmed COVID-19 in Saudi Arabia.

MeSH terms

  • Adult
  • Aged
  • Antiviral Agents / therapeutic use
  • Betacoronavirus / isolation & purification
  • COVID-19
  • Coronavirus Infections / diagnostic imaging
  • Coronavirus Infections / pathology*
  • Coronavirus Infections / therapy
  • Coronavirus Infections / virology
  • Diabetes Complications
  • Female
  • Hospitalization
  • Humans
  • Hypertension / complications
  • Intensive Care Units
  • Macrolides / therapeutic use
  • Male
  • Middle Aged
  • Pandemics
  • Pneumonia, Viral / diagnostic imaging
  • Pneumonia, Viral / pathology*
  • Pneumonia, Viral / therapy
  • Pneumonia, Viral / virology
  • Retrospective Studies
  • SARS-CoV-2
  • Saudi Arabia
  • Severity of Illness Index
  • Thorax / diagnostic imaging

Substances

  • Antiviral Agents
  • Macrolides

Grants and funding

The author(s) received no specific funding for this work.