Surgical resection and liposomal amphotericin B to treat cavitary pulmonary zygomycosis in a patient with diabetes

Respir Care. 2011 Nov;56(11):1837-9. doi: 10.4187/respcare.01119. Epub 2011 May 20.

Abstract

We describe a 24-year-old man with type 1 diabetes mellitus and a cavitary lesion in the right upper lobe, caused by a zygomycete. Surgical resection plus liposomal amphotericin B therapy was successful. We discuss predisposing condition, clinical findings, diagnosis, and treatment of pulmonary zygomycosis.

Publication types

  • Case Reports

MeSH terms

  • Amphotericin B / administration & dosage*
  • Antifungal Agents / administration & dosage*
  • Comorbidity
  • Diabetes Mellitus / epidemiology*
  • Humans
  • Immunocompromised Host
  • Liposomes
  • Lung Diseases, Fungal / drug therapy
  • Lung Diseases, Fungal / epidemiology*
  • Lung Diseases, Fungal / surgery
  • Lung Diseases, Fungal / therapy*
  • Male
  • Young Adult
  • Zygomycosis / drug therapy
  • Zygomycosis / epidemiology*
  • Zygomycosis / surgery
  • Zygomycosis / therapy*

Substances

  • Antifungal Agents
  • Liposomes
  • Amphotericin B