Background Whether noninvasive ventilation should be administered in patients with acute
hypoxemic respiratory failure is debated. Therapy with high-flow oxygen through a nasal …

Background Awake prone positioning has been reported to improve oxygenation for patients
with COVID-19 in retrospective and observational studies, but whether it improves patient-…

Objective The incidence, pathophysiology, and consequences of patient-ventilator asynchrony
are poorly known. We assessed the incidence of patient-ventilator asynchrony during …

Rationale: Baseline characteristics and management have changed over time in patients
requiring mechanical ventilation; however, the impact of these changes on patient outcomes is …

Objective: Extubation failure is associated with a poor prognosis, but the respective roles for
reintubation per se and underlying disease severity remain unclear. Our objectives were to …

The day of extubation is a critical time during an intensive care unit (ICU) stay. Extubation is
usually decided after a weaning readiness test involving spontaneous breathing on a T-…

Rationale: A revised definition of clinical criteria for acute respiratory distress syndrome (ARDS),
the Berlin definition, was recently established to classify patients according to their …

Objectives: A low or moderate expired tidal volume can be difficult to achieve during noninvasive
ventilation for de novo acute hypoxemic respiratory failure (ie, not due to exacerbation …

Purpose High flow nasal cannula (HFNC) is a relatively recent respiratory support technique
which delivers high flow, heated and humidified controlled concentration of oxygen via the …

Objective To determine the prevalence of patient–ventilator asynchrony in patients receiving
non-invasive ventilation (NIV) for acute respiratory failure. Design Prospective multicenter …