The future of cystic fibrosis care: a global perspective

…, C Castaños, C Castellani, CA Byrnes… - The Lancet …, 2020 - thelancet.com
The past six decades have seen remarkable improvements in health outcomes for people
with cystic fibrosis, which was once a fatal disease of infants and young children. However, …

Effect of Bronchoalveolar Lavage–directed therapy on Pseudomonas aeruginosa infection and structural lung injury in children with Cystic Fibrosis: A randomized trial

CE Wainwright, S Vidmar, DS Armstrong, CA Byrnes… - Jama, 2011 - jamanetwork.com
Context Early pulmonary infection in children with cystic fibrosis leads to increased morbidity
and mortality. Despite wide use of oropharyngeal cultures to identify pulmonary infection, …

[PDF][PDF] Chronic suppurative lung disease and bronchiectasis in children and adults in Australia and New Zealand Thoracic Society of Australia and New Zealand …

…, PJ Torzillo, PT King, GP Maguire, CA Byrnes… - Medical Journal of …, 2015 - mja.com.au
Catherine A Byrnes … 3 Chang AB, Bell SC, Byrnes CA, et al. Chronic suppurative lung
disease and bronchiectasis in children and adults in Australian and New Zealand. A position …

Long-term azithromycin for Indigenous children with non-cystic-fibrosis bronchiectasis or chronic suppurative lung disease (Bronchiectasis Intervention Study): a …

PC Valery, PS Morris, CA Byrnes… - The lancet Respiratory …, 2013 - thelancet.com
Background Indigenous children in high-income countries have a heavy burden of
bronchiectasis unrelated to cystic fibrosis. We aimed to establish whether long-term azithromycin …

[HTML][HTML] The global impact of SARS-CoV-2 in 181 people with cystic fibrosis

…, K Brownlee, S Ahern, PR Burgel, CA Byrnes… - Journal of cystic …, 2020 - Elsevier
With the growing SARS-CoV-2 pandemic, we need to better understand its impact in specific
patient groups like those with Cystic Fibrosis (CF). We report on 181 people with CF (32 …

Indigenous children from three countries with non‐cystic fibrosis chronic suppurative lung disease/bronchiectasis

…, PC Valery, P Morris, CA Byrnes… - Pediatric …, 2014 - Wiley Online Library
Objective Indigenous children in developed countries are at increased risk of chronic suppurative
lung disease (CSLD), including bronchiectasis. We evaluated sociodemographic and …

[HTML][HTML] COVID-19 and infant hospitalizations for seasonal respiratory virus infections, New Zealand, 2020

…, S Taylor, S Ameratunga, CA Byrnes - Emerging Infectious …, 2021 - ncbi.nlm.nih.gov
In March 2020, a national elimination strategy for coronavirus disease was introduced in New
Zealand. Since then, hospitalizations for lower respiratory tract infection among infants< 2 …

Prospective evaluation of respiratory exacerbations in children with cystic fibrosis from newborn screening to 5 years of age

CA Byrnes, S Vidmar, JL Cheney, JB Carlin… - Thorax, 2013 - thorax.bmj.com
Background Newborn screening allows novel treatments for cystic fibrosis (CF) to be trialled
in early childhood before irreversible lung injury occurs. As respiratory exacerbations are a …

[HTML][HTML] Amoxicillin–clavulanate versus azithromycin for respiratory exacerbations in children with bronchiectasis (BEST-2): a multicentre, double-blind, non-inferiority …

V Goyal, K Grimwood, CA Byrnes, PS Morris… - The Lancet, 2018 - thelancet.com
Background Although amoxicillin–clavulanate is the recommended first-line empirical oral
antibiotic treatment for non-severe exacerbations in children with bronchiectasis, azithromycin …

[HTML][HTML] Pseudomonas aeruginosa genotypes acquired by children with cystic fibrosis by age 5-years

…, AJ Martin, B Whitehead, J Hunter, CA Byrnes… - Journal of Cystic …, 2015 - Elsevier
Background We describe Pseudomonas aeruginosa acquisitions in children with cystic
fibrosis (CF) aged ≤ 5-years, eradication treatment efficacy, and genotypic relationships …