Self-extubations: a 12-month experience

DP Coppolo, JJ May - Chest, 1990 - Elsevier
Unplanned removal of an endotracheal airway tube by a patient (SXT) represents a potentially
life-threatening incident. Prospective monitoring of all intubated adult ICU patients for one …

Electrostatics and inhaled medications: influence on delivery via pressurized metered-dose inhalers and add-on devices

JP Mitchell, DP Coppolo, MW Nagel - Respiratory care, 2007 - rc.rcjournal.com
The movement of inhaler-generated aerosols is significantly influenced by electrostatic
charge on the particles and on adjacent surfaces. Particle charging arises in the aerosol …

[HTML][HTML] Non-pharmaceutical techniques for obstructive airway clearance focusing on the role of oscillating positive expiratory pressure (OPEP): a narrative review

DP Coppolo, J Schloss, JA Suggett, JP Mitchell - Pulmonary Therapy, 2022 - Springer
Mucus secretion in the lungs is a natural process that protects the airways from inhaled
insoluble particle accumulation by capture and removal via the mucociliary escalator. Diseases …

The importance of nonelectrostatic materials in holding chambers for delivery of hydrofluoroalkane albuterol

JL Rau, DP Coppolo, MW Nagel… - Respiratory …, 2006 - rc.rcjournal.com
INTRODUCTION: Electrostaticattraction of aerosolized particles to the inner walls of an
aerosol holding chamber (HC) made from a nonconducting material can reduce medication …

Impact of oscillating positive expiratory pressure device use on post-discharge hospitalizations: a retrospective cohort study comparing patients with COPD or chronic …

J Tse, K Wada, Y Wang, D Coppolo… - … Journal of Chronic …, 2020 - Taylor & Francis
Purpose Managing and preventing disease exacerbations are key goals of COPD care.
Oscillating positive expiratory pressure (OPEP) devices have been shown to improve clinical …

A novel, versatile valved holding chamber for delivering inhaled medications to neonates and small children: laboratory simulation of delivery options

RM DiBlasi, DP Coppolo, MW Nagel, CC Doyle… - Respiratory …, 2010 - rc.rcjournal.com
BACKGROUND: Delivery of bronchodilator to infants and small children from a pressurized
metered-dose inhaler with valved holding chamber (pMDI-VHC) is limited by airway …

[HTML][HTML] A real-world study of 30-day exacerbation outcomes in chronic obstructive pulmonary disease (COPD) patients managed with Aerobika OPEP

…, P Dunne, G Kauffman, B Carlin, D Coppolo… - Pulmonary …, 2017 - Springer
Introduction Oscillating positive expiratory pressure (OPEP) devices may reduce chronic
symptoms in patients with obstructive pulmonary disease (COPD); however, no real-world …

[HTML][HTML] A Retrospective Study of the Effectiveness of the AeroChamber Plus® Flow-Vu® Antistatic Valved Holding Chamber for Asthma Control

C Burudpakdee, V Kushnarev, D Coppolo… - Pulmonary Therapy, 2017 - Springer
Introduction Electrostatic charge in valved holding chambers (VHCs) may lead to inconsistent
metered-dose inhaler (MDI) asthma drug delivery. We compared the AeroChamber Plus ® …

Cost-effectiveness of the Aerobika* oscillating positive expiratory pressure device in the management of COPD exacerbations

…, S Kowal, JA Suggett, DP Coppolo - … journal of chronic …, 2017 - Taylor & Francis
Introduction COPD places a huge clinical and economic burden on the US health care
system, with acute exacerbations representing a key driver of direct medical costs. Current …

Levalbuterol aerosol delivery with a nonelectrostatic versus a nonconducting valved holding chamber

DP Coppolo, JP Mitchell, MW Nagel - Respiratory care, 2006 - rc.rcjournal.com
BACKGROUND: Hydrofluoroalkane-propelled levalbuterol (Xopenex) aerosol is a recently
approved formulation for delivery via metered-dose inhaler for the treatment or prevention of …