Cryptococcal dissemination to the central nervous system requires the vacuolar calcium transporter Pmc1
ED Squizani, NK Oliveira, JCV Reuwsaat… - Cellular …, 2018 - Wiley Online Library
Cryptococcus neoformans is a basidiomycetous yeast and the cause of cryptococcosis in
immunocompromised individuals. The most severe form of the disease is meningoencephalitis, …
immunocompromised individuals. The most severe form of the disease is meningoencephalitis, …
Calcium: A central player in Cryptococcus biology
ED Squizani, JCV Reuwsaat, H Motta, A Tavanti… - Fungal Biology …, 2021 - Elsevier
… Author links open overlay panel Eamim D. Squizani a 1 , Júlia CV Reuwsaat a 1 , Heryk …
to transmigrate and survive within the brain parenchyma (Squizani et al., 2018). Meanwhile, a …
to transmigrate and survive within the brain parenchyma (Squizani et al., 2018). Meanwhile, a …
Immediate effects of chest physiotherapy on hemodynamic, metabolic, and oxidative stress parameters in subjects with septic shock
…, DAS Melo, FB Nunes, FS Dias, ED Squizani… - Respiratory …, 2014 - rc.rcjournal.com
BACKGROUND: Septic shock presents as a continuum of infectious events, generating
tissue hypoxia and hypovolemia, and increased oxidative stress. Chest physiotherapy helps …
tissue hypoxia and hypovolemia, and increased oxidative stress. Chest physiotherapy helps …
[HTML][HTML] Genotypic and Phenotypic Diversity of Cryptococcus gattii VGII Clinical Isolates and Its Impact on Virulence
…, ACL Fontes, JCV Reuwsaat, ED Squizani… - Frontiers in …, 2018 - frontiersin.org
The Cryptococcus gattii species complex harbors the main etiological agents of cryptococcosis
in immunocompetent patients. C. gattii molecular type VGII predominates in the north and …
in immunocompetent patients. C. gattii molecular type VGII predominates in the north and …
[HTML][HTML] Insights into the Multi-Azole Resistance Profile in Candida haemulonii Species Complex
…, LS Ramos, SSC Oliveira, LB Magalhães, ED Squizani… - Journal of Fungi, 2020 - mdpi.com
The Candida haemulonii complex (C. duobushaemulonii, C. haemulonii, and C. haemulonii
var. vulnera) is composed of emerging, opportunistic human fungal pathogens able to …
var. vulnera) is composed of emerging, opportunistic human fungal pathogens able to …
New nanotechnological formulation based on amiodarone-loaded lipid core nanocapsules displays anticryptococcal effect
NK Oliveira, LA Frank, ED Squizani… - European Journal of …, 2021 - Elsevier
Cryptococcus neoformans is the etiological agent of cryptococcal meningoencephalitis. The
recommended available treatment has low efficiency, with high toxicity and resistance as …
recommended available treatment has low efficiency, with high toxicity and resistance as …
The small heat shock protein Hsp12. 1 has a major role in the stress response and virulence of Cryptococcus gattii
H Motta, JCV Reuwsaat, ED Squizani… - Fungal Genetics and …, 2023 - Elsevier
Cryptococcus gattii is one of the etiological agents of cryptococcosis. To achieve a successful
infection, C. gattii cells must overcome the inhospitable host environment and deal with the …
infection, C. gattii cells must overcome the inhospitable host environment and deal with the …
A predicted mannoprotein participates in Cryptococcus gattii capsular structure
… (D) Fungal load in mouse lungs collected 24 or 48 h postinfection with C. gattii WT and …
melanization (C) and agar containing egg yolk emulsion to evaluate phospholipase activity (D). …
melanization (C) and agar containing egg yolk emulsion to evaluate phospholipase activity (D). …
Calcium binding protein Ncs1 is Calcineurin regulated in Cryptococcus neoformans and essential for cell division and virulence
ED Squizani, JCV Reuwsaat, S Lev, H Motta… - Msphere, 2020 - Am Soc Microbiol
Intracellular calcium (Ca 2+ ) is crucial for signal transduction in Cryptococcus neoformans ,
the major cause of fatal fungal meningitis. The calcineurin pathway is the only Ca 2+ -…
the major cause of fatal fungal meningitis. The calcineurin pathway is the only Ca 2+ -…
Fructose-1, 6-bisphosphate reverts iron-induced phenotype of hepatic stellate cells by chelating ferrous ions
HB Dias, GC Krause, ED Squizani, KG Lima… - Biometals, 2017 - Springer
Hepatic fibrosis is an extracellular matrix deposition by hepatic stellate cells (HSC). Fibrosis
can be caused by iron, which will lead to hydroxyl radical production and cell damage. …
can be caused by iron, which will lead to hydroxyl radical production and cell damage. …