User profiles for Edward Shepherd

Edward Shepherd

- Verified email at nationwidechildrens.org - Cited by 3152

Edward Shepherd

- Verified email at cardiff.ac.uk - Cited by 337

MAPK phosphatases—regulating the immune response

Y Liu, EG Shepherd, LD Nelin - Nature Reviews Immunology, 2007 - nature.com
Mitogen-activated protein kinase (MAPK) phosphatases (MKPs) are protein phosphatases
that dephosphorylate both the phosphothreonine and phosphotyrosine residues on activated …

Interdisciplinary care of children with severe bronchopulmonary dysplasia

SH Abman, JM Collaco, EG Shepherd… - The Journal of …, 2017 - jpeds.com
Advances in perinatal care have dramatically im-proved survival of extremely preterm infants
and the incidence of bronchopulmonary dysplasia (BPD) has not changed over the past …

Effect of depth and duration of cooling on deaths in the NICU among neonates with hypoxic ischemic encephalopathy: a randomized clinical trial

…, CMP Huitema, M Garg, RA Ehrenkranz, EG Shepherd… - Jama, 2014 - jamanetwork.com
Importance Hypothermia at 33.5C for 72 hours for neonatal hypoxic ischemic encephalopathy
reduces death or disability to 44% to 55%; longer cooling and deeper cooling are …

Effect of depth and duration of cooling on death or disability at age 18 months among neonates with hypoxic-ischemic encephalopathy: a randomized clinical trial

…, JE Brumbaugh, KL Watterberg, EG Shepherd… - Jama, 2017 - jamanetwork.com
Importance Hypothermia for 72 hours at 33.5C for neonatal hypoxic-ischemic encephalopathy
reduces death or disability, but rates continue to be high. Objective To determine if cooling …

[HTML][HTML] The role of mitogen-activated protein kinase phosphatase-1 in the response of alveolar macrophages to lipopolysaccharide: attenuation of proinflammatory …

Q Zhao, EG Shepherd, ME Manson, LD Nelin… - Journal of Biological …, 2005 - ASBMB
Mitogen-activated protein (MAP) kinases are critical mediators of innate immune responses.
In response to lipopolysaccharide (LPS), MAP kinases are rapidly activated and play an …

Infant pulmonary function testing and phenotypes in severe bronchopulmonary dysplasia

EG Shepherd, BJ Clouse, KA Hasenstab… - …, 2018 - publications.aap.org
BACKGROUND: The definition of severe bronchopulmonary dysplasia (sBPD) is based on
respiratory support needs. The management of a patient with sBPD remains empirical and is …

[HTML][HTML] The function of mitogen-activated protein kinase phosphatase-1 in peptidoglycan-stimulated macrophages

EG Shepherd, Q Zhao, SE Welty, TN Hansen… - Journal of Biological …, 2004 - ASBMB
Mitogen-activated protein (MAP) kinases play a pivotal role in the macrophages in the production
of proinflammatory cytokines triggered by lipopolysaccharides. However, their function …

Policy shifts, developer contributions and land value capture in London 2005–2017

P McAllister, E Shepherd, P Wyatt - Land use policy, 2018 - Elsevier
Since the early 1990s developer contributions have been the main instrument for land value
capture by local government in the UK. There has been little empirical research that has …

Significant reduction of central-line associated bloodstream infections in a network of diverse neonatal nurseries

EG Shepherd, TJ Kelly, JA Vinsel… - The Journal of …, 2015 - Elsevier
Objective To describe a quality improvement (QI) initiative that was associated with a dramatic
reduction in neonatal central-line associated bloodstream infection (CLABSI) rate in a …

Tracheostomy placement in infants with bronchopulmonary dysplasia: safety and outcomes

…, M Malkar, SE Welty, R Brown, E Shepherd… - Pediatric …, 2013 - Wiley Online Library
Optimizing the timing and safety for the placement of a tracheostomy in infants with
bronchopulmonary dysplasia (BPD) has not been determined. The purpose of the present study was …