Airway clearance therapy (ACT) is used in a variety of settings for a variety of ailments.
These guidelines were developed from a systematic review with the purpose of determining …

Aerosolized medications are used as airway clearance therapy to treat a variety of airway
diseases. These guidelines were developed from a systematic review with the purpose of …

Dry powder inhalers (DPIs) are breath actuated, and patients using DPIs need to generate
an optimal inspiratory flow during the inhalation maneuver for effective drug delivery to the …

BACKGROUND: Bench and clinical data indicate that techniques for applying noninvasive
respiratory support may vary in terms of effectiveness, application, and tolerability. We …

BACKGROUND: Tiotropium is used in maintenance treatment of chronic obstructive pulmonary
disease (COPD), but there are no guidelines on when to start tiotropium following an …

BACKGROUND: Acute respiratory failure is among the sequelae of complications that can
develop in response to severe sepsis. Research into sepsis-related respiratory failure has …

BACKGROUND: COVID-19 is associated with variable symptoms and clinical sequelae.
Studies have examined the clinical course of these patients, finding a prolonged need for …

COPD is a chronic and progressive disease associated with poor quality of life and an
increased risk of psychological distress. 1 While the physical and psychosocial impact of end-…

Background The design of a multi-center randomized controlled trial (RCT) involves multiple
considerations, such as the choice of the sample size, the number of centers and their …

Methods: Multicenter, retrospective study of all patients intubated in the ED with a P/F ratio≥
300. Data were entered into REDCap, including demographic and clinical information. High …