Rationale: Ventilation in the prone position for about 7 h/d in patients with acute respiratory
distress syndrome (ARDS), acute lung injury, or acute respiratory failure does not decrease …

Importance Studies of mechanically ventilated critically ill patients that combine populations
that are at high and low risk for reintubation suggest that conditioned high-flow nasal …

Objective To evaluate incidence, factors associated with unplanned endotracheal extubation
(UEE), and prognostic factors for reintubation. Design

There is limited information available describing the clinical and epidemiological features of
Spanish patients requiring hospitalization for coronavirus disease 2019 (COVID-19). In this …

Background Extubation failure is associated with increased morbidity and mortality, but cannot
be safely predicted or avoided. High-flow nasal cannula (HFNC) prevents postextubation …

Inhaled nitric oxide (NO) and prone position (PP) are frequently used in the treatment of
acute respiratory distress syndrome (ARDS). We compared the gas exchange and …

Background During the first wave of the COVID-19 pandemic, shortages of ventilators and
ICU beds overwhelmed health care systems. Whether early tracheostomy reduces the …

OBJECTIVE: In obesity-hypoventilation-syndrome patients mechanically ventilated for
hypercapnic respiratory failure we investigated the relationship between CO 2 response, body …

Purpose This study aimed to determine the best strategy to achieve fast and safe extubation.
Methods This multicenter trial randomized patients with primary respiratory failure and low-…

BACKGROUND: The ventilatory capacity of the respiratory neuromuscular system can be
studied with the hypercapnia test. OBJECTIVE: To determine whether decreased response to …