Importance Data on the association of COVID-19 vaccination with intensive care unit (ICU)
admission and outcomes of patients with SARS-CoV-2–related pneumonia are scarce. …

Critically ill patients exhibit reduced melatonin secretion, both in nocturnal peaks and basal
daytime levels. Oral melatonin supplementation may be useful for known sedative and …

Background Early revascularization of ischemic organs is key to improving outcomes, yet
consequent reperfusion injury may be harmful. Reperfusion injury is largely attributed to …

Oxygen administration is particularly relevant in patients undergoing surgery under general
anesthesia and in those who suffer from acute or critical illness. Nevertheless, excess O2, or …

Oxygen (O 2 ) is commonly used in clinical practice to prevent or treat hypoxia, but if used in
excess (hyperoxia), it may act as toxic. O 2 toxicity arises from the enhanced formation of …

In this study, the aim was to test the biochemical effects of melatonin supplementation in
Intensive Care Unit (ICU) patients, since their blood levels are decreased. Sixty-four patients …

PURPOSE: The aim of this study is to evaluate continuous wrist actigraphy (measurement of
limb movements) in intensive care unit patients as a neurologic status monitoring. …

The diagnosis of sepsis is often difficult and belated, substantially increasing mortality in
affected patients. Its early identification allows for us to choose the most appropriate therapies in …

Background and objectives: Cancer pain affects patients at all stages of the disease and
there are clear guidelines for its management. Morphine is considered the first-choice strong …

BACKGROUND: International guidelines recommend systematic assessment of pain,
agitation/sedation and delirium with validated scales for all ICU patients. However, these …