OBJECTIVE: To develop comprehensive clinical practice guidelines for critically ill infants
and children, with specific attention to seven domains of care including pain, sedation/agitation…

Background: We sought to compare the efficacy of midazolam versus dexmedetomidine for
sedation during mechanical ventilation in infants and children. Methods: We performed a …

We present preliminary clinical experience with the use of dexmedetomidine, an α 2 adrenergic
agonist, in children. Dexmedetomidine was administered in three clinical scenarios: (i) to …

Background : Flexible fiberoptic bronchoscopy is an important diagnostic tool for pediatric
pulmonologists. Because of its favorable respiratory profile, ketamine has become a popular …

Objective: Children often require sedation for lengthy noninvasive procedures. Conventional
agents such as chloral hydrate, benzodiazepines, or barbiturates have been associated …

In patients who are mechanically ventilated in the pediatric intensive care unit (PICU),
sedative and/or analgesic medications are routinely provided and titrated to effect based on …

… Tobias JD, Berkenbosch JW: Initial experience with dexmedetomidine in pediatric-aged
patients. Paediatr Anaesth 2002; 12: 171–175 … Other articles in this journal by John W …

Background : Oral premedication is often required in children to provide anxiolysis and lessen
the psychological impact of hospitalization and/or procedures. We present our experience …

Dexmedetomidine has been increasingly in use for pediatric noninvasive procedural
sedation. This retrospective study examined experience in children with autism and other …

Cyclic vomiting syndrome (CVS) is a chronic, recurrent disorder of unknown etiology characterized
by episodes of nausea and vomiting lasting hours or days and separated by symptom…