Transient receptor potential vanilloid 4–mediated disruption of the alveolar septal barrier: a novel mechanism of acute lung injury

DF Alvarez, JA King, D Weber, E Addison… - Circulation …, 2006 - Am Heart Assoc
Disruption of the alveolar septal barrier leads to acute lung injury, patchy alveolar flooding,
and hypoxemia. Although calcium entry into endothelial cells is critical for loss of barrier …

The cancer paradigm of severe pulmonary arterial hypertension

PR Rai, CD Cool, JAC King, T Stevens… - American journal of …, 2008 - atsjournals.org
The plexiform lesions of severe pulmonary arterial hypertension (PAH) are similar in histologic
appearance, whether the disease is idiopathic or secondary. Both forms of the disease …

Lung microvascular endothelium is enriched with progenitor cells that exhibit vasculogenic capacity

DF Alvarez, L Huang, JA King… - … of Physiology-Lung …, 2008 - journals.physiology.org
Endothelial progenitor cells (EPCs) have been isolated postnatally from bone marrow, blood,
and both the intima and adventitia of conduit vessels. However, it is unknown whether …

TRPV4 initiates the acute calcium-dependent permeability increase during ventilator-induced lung injury in isolated mouse lungs

…, MI Townsley, AB Al-Mehdi, JA King… - … of Physiology-Lung …, 2007 - journals.physiology.org
We have previously implicated calcium entry through stretch-activated cation channels in
initiating the acute pulmonary vascular permeability increase in response to high peak inflation …

TRPV4 channels augment macrophage activation and ventilator-induced lung injury

…, MY Jian, MI Townsley, JA King… - … of Physiology-Lung …, 2010 - journals.physiology.org
We have previously implicated transient receptor potential vanilloid 4 (TRPV4) channels
and alveolar macrophages in initiating the permeability increase in response to high peak …

Activated leukocyte cell adhesion molecule: a new paradox in cancer

SF Ofori-Acquah, JA King - Translational Research, 2008 - Elsevier
The activated leukocyte cell adhesion molecule [ALCAM/CD166/melanoma metastasis
clone D (MEMD)] is an immunoglobulin superfamily cell adhesion molecule. It is expressed …

Evolutionary aspects of gonadotropin-releasing hormone and its receptor

JA King, RP Millar - Cellular and molecular neurobiology, 1995 - Springer
Gonadotropin-releasing hormone (GnRH) was originally isolated as a hypothalamic peptide
hormone that regulates the reproductive system by stimulating the release of gonadotropins …

High vascular pressure–induced lung injury requires P450 epoxygenase–dependent activation of TRPV4

MY Jian, JA King, AB Al-Mehdi, W Liedtke… - American journal of …, 2008 - atsjournals.org
High vascular pressure targets the lung septal network, causing acute lung injury. While
calcium entry in septal endothelium has been implicated, the channel involved is not known. …

Structure of chicken hypothalamic luteinizing hormone-releasing hormone. II. Isolation and characterization.

JA King, RP Millar - Journal of Biological Chemistry, 1982 - ASBMB
Avian luteinizing hormone-releasing hormone (LH-RH) has been isolated from 249,000
chicken hypothalami and shown to differ structurally from mammalian hypothalamic LH-RH. …

[HTML][HTML] Activated leukocyte cell adhesion molecule in breast cancer: prognostic indicator

JA King, SF Ofori-Acquah, T Stevens… - Breast Cancer …, 2004 - Springer
Introduction Activated leukocyte cell adhesion molecule (ALCAM) (CD166) is an immunoglobulin
molecule that has been implicated in cell migration. The present study examined the …