Influence of rheologic changes and platelet–neutrophil interactions on cell filtration in sepsis

LA Kirschenbaum, M Aziz, ME Astiz… - American journal of …, 2000 - atsjournals.org
We examined the role of erythrocyte (red blood cell; RBC) aggregation and deformability,
neutrophil (polymorphonuclear neutrophil; PMN) deformability, whole-blood viscosity, and …

The experience at St. Vincent's Hospital, Manhattan, on September 11, 2001: preparedness, response, and lessons learned

L Kirschenbaum, A Keene, P O'Neill… - Critical care …, 2005 - journals.lww.com
St. Vincent’s Hospital in New York City was the primary recipient of patients after the 1993
bombing of the World Trade Center. This experience prompted the drafting of a formal disaster …

Microvascular response in patients with cardiogenic shock

LA Kirschenbaum, ME Astiz, EC Rackow… - Critical care …, 2000 - journals.lww.com
Objective: To examine the mechanisms contributing to decreased microvascular blood flow
in cardiogenic shock by comparing patients with cardiogenic shock with critically ill controls …

Effect of continuous lateral rotational therapy on the prevalence of ventilator-associated pneumonia in patients requiring long-term ventilatory care

L Kirschenbaum, E Azzi, T Sfeir, P Tietjen… - Critical care …, 2002 - journals.lww.com
Effect of continuous lateral rotational therapy on the preva... : Critical Care Medicine Effect of
continuous lateral rotational therapy on the prevalence of ventilator-associated pneumonia in …

Importance of platelets and fibrinogen in neutrophil-endothelial cell interactions in septic shock

LA Kirschenbaum, D McKevitt, M Rullan… - Critical care …, 2004 - journals.lww.com
Objective: To examine the role of platelets, fibrin, and adhesion molecules in mediating
neutrophil-endothelial cell interactions in septic shock. Design: Controlled experiments using …

Impact of timing of tocilizumab use in hospitalized patients with SARS-CoV-2 infection

…, SP Dechario, B Mina, K Singh, L Kirschenbaum… - Respiratory …, 2021 - rc.rcjournal.com
BACKGROUND: SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) continues
to be a global challenge due to the lack of definitive treatment strategies. We sought to …

Augmentation of platelet and endothelial cell eNOS activity decreases sepsis-related neutrophil-endothelial cell interactions

R Khan, LA Kirschenbaum, C LaRow, G Berna… - Shock, 2010 - journals.lww.com
NO is an important mediator of microvascular patency and blood flow. The purpose of this
study was to examine the role of enhanced eNOS activity in attenuating sepsis-induced …

Mechanisms of platelet-neutrophil interactions and effects on cell filtration in septic shock

LA Kirschenbaum, D Adler, ME Astiz, RS Barua… - Shock, 2002 - journals.lww.com
We examined the mechanisms and the adhesive molecules mediating platelet-neutrophil
adhesion in patients with septic shock. Neutrophils, platelets, and platelet poor plasma (NPPP) …

The effect of resuscitation fluids on neutrophil-endothelial cell interactions in septic shock

R Khan, LA Kirschenbaum, C LaRow, ME Astiz - Shock, 2011 - journals.lww.com
Fluid resuscitation is essential in the treatment of septic shock. This study examined the effect
of resuscitative fluids (RFs) on sepsis-induced neutrophil-endothelial cell interactions. The …

Improved clinical outcomes combining house staff self-assessment with an audit-based quality improvement program

L Kirschenbaum, S Kurtz, M Astiz - Journal of general internal medicine, 2010 - Springer
BACKGROUND There is a focus on integrating quality improvement with medical education
and advancement of the American College of Graduate Medical Education (ACGME) core …