Apnea testing during brain death assessment: a review of clinical practice and published literature

JB Scott, MA Gentile, SN Bennett, MA Couture… - Respiratory …, 2013 - rc.rcjournal.com
The diagnosis of brain death is a complex process. Strong knowledge of neurophysiology
and an understanding of brain death etiology must be used to confidently determine brain …

539: SAFETY FIRST: CARBOGEN AND CAPNOGRAPHY USE MINIMIZES COMPLICATIONS DURING APNEA TESTING

J Pepe, A Wolffing, MA Couture, R Brautigam… - Critical Care …, 2014 - journals.lww.com
Methods: After IRB approval, from May 2013 through April 2014 demographic and physiologic
data from sequential ICU patients determined to be brain dead were entered into a data …

PaO2/FIO2 is not a Guesstimation

MA Couture - Respiratory Care, 2017 - rc.rcjournal.com
… We thank Ms Couture for her interest and for commenting on our work.We agree that PaO2/…
Ms Couture found that a patient with acute hypoxemic respiratory failure had an SpO2 of 89…

Dead space fraction: one of many choices to assess PEEP titration

MA Couture - Respiratory Care, 2013 - rc.rcjournal.com
In their prospective trial on PEEP titration following recruitment maneuver in patients with
ARDS, Fengmei et al provided a well controlled study on the effects of the ratio of dead space …

379: CAN AN IN VIVO HANDS-ON LEARNING EXPERIENCE ON LUNG-PROTECTIVE VENTILATION MODIFY CLINICAL PRACTICE?

…, G Nieman, N Habashi, MA Couture… - Critical Care …, 2018 - journals.lww.com
Methods: Sixteen respiratory care professionals from the US discussed concepts related to
the optimal MBp over 3 days and participated an in vivo study of two pediatric and two adult …

626: THE USE OF A NON-DISPOSABLE VS. DISPOSABLE MANOMETER IN TRACHEAL MANOMETRY

R Pylant, N Silva, MA Couture - Critical Care Medicine, 2012 - journals.lww.com
Introduction: Tracheostomy tube manometry allows objective evaluation of intra-tracheal
pressures during the use of a speaking valve. The use of tracheal manometry promptly …

Development and analysis of recombinant adenoviruses for gene therapy of cystic fibrosis

DP Rich, LA Couture, LM Cardoza… - Human Gene …, 1993 - liebertpub.com
A new adenovirus-based vector (Ad2/CFTR-1) has been constructed in which the cDNA
encoding the cystic fibrosis transmembrane conductance regulator (CFTR), the cystic fibrosis (…

Correction of cAMP-Stimulated Fluid Secretion in Cystic Fibrosis Airway Epithelia: Efficiency of Adenovirus-Mediated Gene Transfer In Vitro

J Zabner, LA Couture, AE Smith, MJ Welsh - Human gene therapy, 1994 - liebertpub.com
Adenovirus vectors are a promising vehicle to deliver cystic fibrosis transmembrane conductance
regulator (CFTR) cDNA to airway epithelia. However, the value of adenovirus vectors …

Characterization of factors involved in modulating persistence of transgene expression from recombinant adenovirus in the mouse lung

…, PA Peterson, SC Wadsworth, KK Couture… - Human gene …, 1997 - liebertpub.com
One potential limitation of adenovirus (Ad)-based vectors for the gene therapy of cystic fibrosis
(CF) and other genetic diseases is the transience of expression observed in most in vivo …

Current good manufacturing practice production of an oncolytic recombinant vesicular stomatitis viral vector for cancer treatment

…, W Dang, M Luo, D Hsu, SLC Woo, L Couture - Human gene …, 2011 - liebertpub.com
Vesicular stomatitis virus (VSV) is an oncolytic virus currently being investigated as a
promising tool to treat cancer because of its ability to selectively replicate in cancer cells. To …