User profiles for Michael C Sklar
 | Michael C SklarUniversity of Toronto Verified email at unityhealth.to Cited by 3487 |
Mechanical ventilation–induced diaphragm atrophy strongly impacts clinical outcomes
…, MS Herridge, S Vorona, MC Sklar… - American journal of …, 2018 - atsjournals.org
Rationale: Diaphragm dysfunction worsens outcomes in mechanically ventilated patients,
but the clinical impact of potentially preventable changes in diaphragm structure and function …
but the clinical impact of potentially preventable changes in diaphragm structure and function …
[HTML][HTML] Lung recruitability in COVID-19–associated acute respiratory distress syndrome: a single-center observational study
…, L Chen, C Lu, W Zhang, JA Xia, MC Sklar… - American journal of …, 2020 - atsjournals.org
Methods This was a retrospective, observational study conducted in a 35-bed ICU at Wuhan
Jinyintan Hospital. The institutional ethics review board approved this study (KY-2020-10.02…
Jinyintan Hospital. The institutional ethics review board approved this study (KY-2020-10.02…
Potential for lung recruitment estimated by the recruitment-to-inflation ratio in acute respiratory distress syndrome. A clinical trial
…, N Rittayamai, I Soliman, MC Sklar… - American Journal of …, 2020 - atsjournals.org
Rationale: Response to positive end-expiratory pressure (PEEP) in acute respiratory
distress syndrome depends on recruitability. We propose a bedside approach to estimate …
distress syndrome depends on recruitability. We propose a bedside approach to estimate …
Anticoagulation practices and the prevalence of major bleeding, thromboembolic events, and mortality in venoarterial extracorporeal membrane oxygenation: a …
… Author links open overlay panel Eric Sy MD a b d , Michael C. Sklar MD c , Laurence
Lequier MD e , Eddy Fan MD, PhD f g , Hussein D. Kanji MD, MSc, MPH d h …
Lequier MD e , Eddy Fan MD, PhD f g , Hussein D. Kanji MD, MSc, MPH d h …
Anticoagulation practices during venovenous extracorporeal membrane oxygenation for respiratory failure. A systematic review
Background: The optimal anticoagulation strategy for venovenous extracorporeal membrane
oxygenation (VV-ECMO) is not known. Objectives: To evaluate the safety of anticoagulation …
oxygenation (VV-ECMO) is not known. Objectives: To evaluate the safety of anticoagulation …
Effort to breathe with various spontaneous breathing trial techniques. A physiologic meta-analysis
Rationale: Spontaneous breathing trials (SBTs) are designed to simulate conditions after
extubation, and it is essential to understand the physiologic impact of different methods. …
extubation, and it is essential to understand the physiologic impact of different methods. …
[HTML][HTML] Extracorporeal carbon dioxide removal in patients with chronic obstructive pulmonary disease: a systematic review
MC Sklar, F Beloncle, CM Katsios, L Brochard… - Intensive care …, 2015 - Springer
Introduction Extracorporeal carbon dioxide removal (ECCO 2 R) has been proposed for
hypercapnic respiratory failure in chronic obstructive pulmonary disease (COPD) exacerbations, …
hypercapnic respiratory failure in chronic obstructive pulmonary disease (COPD) exacerbations, …
Assessment of the Clavien‐Dindo classification system for complications in head and neck surgery
E Monteiro, MC Sklar, A Eskander… - The …, 2014 - Wiley Online Library
Objectives/Hypothesis The importance of reporting and grading surgical complications is
central to quality improvement in head and neck surgery. The purpose of this study is to assess …
central to quality improvement in head and neck surgery. The purpose of this study is to assess …
Association of low baseline diaphragm muscle mass with prolonged mechanical ventilation and mortality among critically ill adults
MC Sklar, M Dres, E Fan, GD Rubenfeld… - JAMA network …, 2020 - jamanetwork.com
Importance Low diaphragm muscle mass at the outset of mechanical ventilation may
predispose critically ill patients to poor clinical outcomes. Objective To determine whether lower …
predispose critically ill patients to poor clinical outcomes. Objective To determine whether lower …
Lung recruitment assessed by electrical impedance tomography (RECRUIT): a multicenter study of COVID-19 acute respiratory distress syndrome
…, L Chen, J Dianti, MLA Sousa, MC Sklar… - American Journal of …, 2023 - atsjournals.org
Rationale: Defining lung recruitability is needed for safe positive end-expiratory pressure (PEEP)
selection in mechanically ventilated patients. However, there is no simple bedside …
selection in mechanically ventilated patients. However, there is no simple bedside …