Septic Shock Attributed to Candida Infection: Importance of Empiric Therapy and Source Control

M Kollef, S Micek, N Hampton… - Clinical infectious …, 2012 - academic.oup.com
Background. Delayed treatment of candidemia has previously been shown to be an important
determinant of patient outcome. However, septic shock attributed to Candida infection and …

[HTML][HTML] Fluid balance and cardiac function in septic shock as predictors of hospital mortality

ST Micek, C McEvoy, M McKenzie, N Hampton… - Critical care, 2013 - Springer
Introduction Septic shock is a major cause of morbidity and mortality throughout the world.
Unfortunately, the optimal fluid management of septic shock is unknown and currently is …

Duration of exposure to antipseudomonal β‐lactam antibiotics in the critically ill and development of new resistance

BF Teshome, SM Vouri, N Hampton… - … : The Journal of …, 2019 - Wiley Online Library
Study Objective Minimizing the duration of broad‐spectrum antimicrobial exposure in the
critically ill is a commonly used strategy aimed at preventing resistance. Our objective was to …

A case-control study assessing the impact of nonventilated hospital-acquired pneumonia on patient outcomes

ST Micek, B Chew, N Hampton, MH Kollef - Chest, 2016 - Elsevier
Background Nonventilated hospital-acquired pneumonia (NVHAP) is a serious nosocomial
infection that is increasingly attributed to antibiotic-resistant bacteria. Methods This is a …

Sepsis-associated coagulopathy severity predicts hospital mortality

PG Lyons, ST Micek, N Hampton… - Critical care medicine, 2018 - journals.lww.com
Objectives: To assess whether sepsis-associated coagulopathy predicts hospital mortality.
Design: Retrospective cohort study. Setting: One-thousand three-hundred beds urban …

The accuracy of dental panoramic tomographs in determining the root morphology of mandibular third molar teeth before surgery

…, WD Keen, DJC Stewart, N Hampton - Oral Surgery, Oral …, 2003 - Elsevier
Objective. The objective of this study was to assess the accuracy of dental panoramic tomograph
(DPT) in the presurgical assessment of mandibular third molar teeth by correlating the …

The determinants of hospital mortality among patients with septic shock receiving appropriate initial antibiotic treatment

…, S Micek, J Hoffmann, A Hoban, N Hampton… - Critical care …, 2012 - journals.lww.com
Objective: To identify the determinants of hospital mortality among patients with septic shock
receiving appropriate initial antibiotic treatment. Design: A retrospective cohort study of …

[HTML][HTML] Epidemiology, co-infections, and outcomes of viral pneumonia in adults: an observational cohort study

MP Crotty, S Meyers, N Hampton, S Bledsoe… - Medicine, 2015 - journals.lww.com
Advanced technologies using polymerase-chain reaction have allowed for increased recognition
of viral respiratory infections including pneumonia. Co-infections have been described …

Outcomes associated with de-escalating therapy for methicillin-resistant Staphylococcus aureus in culture-negative nosocomial pneumonia

MC Cowley, DJ Ritchie, N Hampton, MH Kollef… - Chest, 2019 - Elsevier
Background In culture-positive nosocomial pneumonia, de-escalation (DE) from broad-spectrum
empirical antimicrobials to narrower-spectrum agents has shown to decrease broad-…

Prolonged infusion antibiotics for suspected gram-negative infections in the ICU: a before-after study

…, JR Smith, PH Juang, NB Hampton… - Annals of …, 2013 - journals.sagepub.com
BACKGROUND: β-Lactam antibiotics demonstrate time-dependent killing. Prolonged infusion
of these agents is commonly performed to optimize the time the unbound concentration of …